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  • MK-677 Log

    I have used MK677 before and I know what to expect.MK-677 has a long half-life of 24 hours and therefor I will be dosing 30 mgs before bed on empty stomach.The caps are 10mgs.

    I will be judging this on what I noticed from my prior run of MK677.

    I've noticed an increased appetite throughout the day since I started taking it but subsided after 10 days

    I have noticed better sleep/vivid dreams

    I noticed numbness of extremities.Both of my hands were numb

    I noticed my recovery is great

    I noticed smoother skin

    I noticed increase in muscle fullness


    Here is some additional info:

    36% increase in IGF-1 in 14 days:






    In Alzheimer patients, IGF-1 increased 60% in 6 weeks and 72% in 12 months:

    Despite evidence of target engagement as indicated by an increase in serum insulin-like growth factor-1, the human growth hormone secretagogue MK-677 25 mg was ineffective at slowing the rate of progression of Alzheimer disease.




    In young subjects (18-30), MK-677 treatment resulted in an approximately 50% increase in the duration of stage IV and in a more than 20% increase in REM sleep as compared to placebo ( in 14 days).

    Previous studies have indicated the existence of common mechanisms regulating sleep and somatotropic activity. In the present study, we investigated the effects of prolonged treatment with a novel, orally active, growth hormone secretagogue (MK-677) on sleep quality in healthy young and older adults …


    GH increases bone turnover and stimulates osteoblast activity. We hypothesized that administration of MK-677, an orally active GH secretagogue, together with alendronate, a potent inhibitor of bone resorption, would maintain a higher bone formation rate relative to that seen with alendronate alone, …


    Growth hormone (GH) stimulates osteoblasts in vitro and increases bone turnover and stimulates osteoblast activity when given to elderly subjects. Probably a major effect of GH on bone is mediated through stimulation of either circulating or locally produced insulin-like growth factor I (IGF-I). We …




    Other links

    The reversal of diet-induced negative nitrogen balance by GH suggests a possible therapeutic role for GH treatment in catabolic patients. A double-blind, randomized, placebo-controlled, two-period cross-over study was designed to investigate whether MK-677, an orally active nonpeptide mimic of GH-re …


    Obesity is associated with blunted GH secretion, unfavorable body composition, and increased cardiovascular mortality. The objective of this study was to investigate the effects of oral treatment with the GH secretagogue MK-677 on GH secretion and body composition in otherwise healthy obese males. T …

  • #2
    Re: MK-677 Log

    so this stuff increases release of gh, correct?
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    • #3
      Re: MK-677 Log

      Originally posted by guns01 View Post
      so this stuff increases release of gh, correct?
      Yes.

      Comment


      • #4
        Re: MK-677 Log

        Originally posted by joe1313 View Post
        Yes.
        good deal man. if you are or are not going to be making any nutritional changes would be cool to see. i will def be following along, i love learning about these new compounds
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        • #5
          Re: MK-677 Log

          Originally posted by guns01 View Post
          good deal man. if you are or are not going to be making any nutritional changes would be cool to see. i will def be following along, i love learning about these new compounds
          Supplements Being Used: Vitamin D3,Ubiquinol,NOW Digest Platinum Enzyme Formula, Swanson's Probiotics, & Orange OxiMega Fish Oil

          Current Goals: Lean Bulk
          Here are today's meal.

          Breakfast
          16oz 2% milk,1/2 coconut,1/2 cup oats,& 2 scp Chocolate Protein
          4 eggs
          5 strips turkey bacon
          Blueberry muffin with butter

          Lunch
          Smoque BBQ Pulled Pork Platter http://www.smoquebbq.com/index.html
          Cole Slaw
          BBQ Beans
          Banana
          Ice Tea

          Dinner
          Grilled Salmon
          Sweet Potatoes mashed with butter
          Grilled corn on the cob


          More info on MK-677 http://www.evolutionary.org/nutrobal-mk-677-ibutamoren

          Comment


          • #6
            Re: MK-677 Log

            Monday 6/8/2015

            Bench Press
            Set 1 : 65x10
            Set 2 : 65x10
            Set 3 : 130x10
            Set 4 : 130x10
            Set 5 : 130x10
            Set 6 : 130x10
            Set 7 : 130x10
            Set 8 : 130x10
            Set 9 : 130x10
            Set 10: 125 RPT to failure 8,8,6,
            DC stretch
            Total Weight 13,150lbs
            +475 lbs from last week

            Comment


            • #7
              Re: MK-677 Log

              My stats
              Age 49
              5'7"
              174lbs

              Training

              I am doing high reps with DC Stretches on M/F/S Due to past shoulder injury I can not go heavy on my Chest/Shoulder
              I do low reps/high weight Tue/Thu with DC stretch

              Monday: Bench Press Variation
              Tuesday:Squat
              Wednesday:OFF
              Thursday: Deadlift
              Friday: Military Press
              Saturday:Lower Body work

              Comment


              • #8
                Re: MK-677 Log

                looks like you follow a little of the dc approach. i was just talking to gusto about dante this past week and i hadnt seen anyone following his principles in a while. great stuff man, excited to see the outcome on this one
                TGBSupplements REP

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                Use code 'Baby1' for $5 off your order

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                • #9
                  Re: MK-677 Log

                  Originally posted by guns01 View Post
                  looks like you follow a little of the dc approach. i was just talking to gusto about dante this past week and i hadnt seen anyone following his principles in a while. great stuff man, excited to see the outcome on this one
                  I really like the DC idea but sadly I can't follow the routine the way he lays it out.The stretches and RPT is what I like best about it.

                  Comment


                  • #10
                    Re: MK-677 Log

                    Originally posted by joe1313 View Post
                    I really like the DC idea but sadly I can't follow the routine the way he lays it out.The stretches and RPT is what I like best about it.
                    i would do it and just drive the reps as opposed to hitting weight numbers man. you can always tweak it to work around your injuries and limitations. something else you could look into is mountain dog's stuff. it is individualized and not rough on joints at all. may be something you could consider with either one
                    TGBSupplements REP

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                    • #11
                      Re: MK-677 Log

                      workout schedual looks good bro

                      Comment


                      • #12
                        Re: MK-677 Log

                        Watching this - I love logs. Logs are real world instead of theoretical.

                        Comment


                        • #13
                          Re: MK-677 Log

                          Originally posted by guns01 View Post
                          i would do it and just drive the reps as opposed to hitting weight numbers man. you can always tweak it to work around your injuries and limitations. something else you could look into is mountain dog's stuff. it is individualized and not rough on joints at all. may be something you could consider with either one
                          Mountain dog looks interesting.

                          Originally posted by MOUNTAIN-MAN View Post
                          workout schedual looks good bro
                          Hey thanks for following!!

                          Originally posted by cybrsage View Post
                          Watching this - I love logs. Logs are real world instead of theoretical.
                          Welcome!!

                          Comment


                          • #14
                            Re: MK-677 Log

                            Tuesday 6/9/2015 Day 2

                            Squats
                            Set 1 135x5
                            Set 2 135x5
                            Set 3 225x5
                            Set 4 315x5
                            Set 5 335x3
                            Set 6 205x20 Widowmaker Set at about 60% of the 335
                            DC stretch



                            Breakfast
                            16oz 2% milk,1/2 cup oats,1/2 cup blueberries and 2 scoops Vanilla protein
                            4 eggs
                            5 strips turkey bacon
                            1 blueberry bagel with butter

                            Lunch
                            3 turkey breast sandwiches on whole wheat with lettuce and mustard
                            Potato Salad
                            Banana
                            16oz 2% choc milk

                            Dinner
                            2 grilled sirloin burgers w/lettuce,onion,tomato and cheese
                            Grilled Red Potatoes cut in pieces with butter,garlic and onions
                            Strawberry/Banana Smoothie-16oz 2% milk,1/2 cup straw berries and 1 banana

                            Comment


                            • #15
                              Re: MK-677 Log

                              Wednesday 6/10/2015 Day 3 Off Day



                              Breakfast
                              16oz 2% milk,1/2 cup blueberries,1/2 cup oats,& 2 scp Vanilla protein
                              4 eggs
                              5 strips turkey bacon
                              1 onion bagel with garlic/olive oil butter

                              Lunch
                              3 turkey breast sandwiches on whole wheat with mayo,lettuce and tomato
                              Potato Salad
                              Orange
                              16oz 2% choc milk

                              Dinner
                              Meat Loaf made with ground sirloin
                              Mashed Potatoes
                              Green Beans
                              Blueberry smoothie-16oz 2% milk with 1/2 cup blueberry


                              Obsevations so far
                              Hunger-Appetite is up already
                              Deep sleep/Vivid dreams

                              Comment

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