When on clen which should you use or should you use both Taurine and potassium? I have read clen deplets taurine. But then I read taurine mess with insulin sensitivity, to just take potassium. Any opinions?
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Originally posted by Juice Authority
Taurine aids the movement of potassium, sodium, calcium, and magnesium in and out of cells and thus helps generate nerve impulses.
Great, but the reason its used with clen and other beta agonists cramps is because clen depletes taurine levels from the liver thus hindering the conversion of T4 to T3.
Its also a well known fact that taurine decreases insulin resistance (dont know why I said sensitivity, thats why you dont do two things at once) (1)
(1) Haber CA, Lam TK, Yu Z, Gupta N, Goh T, Bogdanovic E, Giacca A, Fantus IG.
N-acetylcysteine (NAC) and taurine prevent hyperglycemia-induced insulin resistance in vivo: possible role of oxidative stress. Am J Physiol Endocrinol Metab. 2003 Jun 10 [Epub ahead of print]
Some more references for those concerned:
Doheny MH, Waterfield CJ, Timbrell JA.
The effects of the beta 2-agonist drug clenbuterol on taurine levels in heart and other tissues in the rat.
Amino Acids. 1998;15(1-2):13-25
Waterfield CJ, Carvalho F, Timbrell JA.
Effect of treatment with beta-agonists on tissue and urinary taurine levels in rats. Mechanism and implications for protection.
Adv Exp Med Biol. 1996;403:233-45.
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