New Insights on How DHA Inhibits Prostate Cancer

[BABY1]

A study looking into the molecular mechanisms of DHA against prostate cancer has uncovered several methods by which DHA helps prevent and even combat prostate cancer.
Changes in the healthy connective tissue that forms the prostate gland occur during prostate cancer and contribute to the spreading of the cancer. These changes are key factors that determine the severity of the problem.
One of the changes involves fibroblasts, which are carpenter cells that naturally build the prostate connective tissue. When cancer sets in these fibroblasts are changes to a different version called myofibroblasts, in turn fueling the growth of cancerous prostate tissue. Researchers found that DHA directly inhibits the conversion of normal fibroblasts into the cancer-promoting myofibroblasts.
Another important factor is that rate that new prostate cancer cells can infiltrate existing healthy prostate tissue, a process called invasiveness. It was also found that DHA directly inhibits the invasiveness of cancerous prostate cells into healthy tissue.
Both of these issues are significant for both prevention and as part of treatment for this issue.


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[Guest]

Re: New Insights on How DHA Inhibits Prostate Cancer

Great natural supplement.Add it to the list of natures cancer cures.

Thanks for the post.

[Guest]

Re: New Insights on How DHA Inhibits Prostate Cancer

Here's more on it..............


DHA

DHA, which is found in fatty fish and other sources, is an omega-3 fatty acid. It is beneficial for pregnant and breastfeeding women, and it may also be useful for people with high cholesterol, heart disease, and other conditions. Since most people do not eat enough fish, DHA is available as a supplement. Potential side effects include bruising, gas, nausea, and prolonged bleeding.


What Is DHA?

DHA (docosahexaenoic acid) is an omega-3 fatty acid. Most comes from marine sources (mainly fatty fish and certain algae and plankton). Because many people do not eat much fish (and since omega-3 fatty acids are recommended as part of a heart-healthy diet), DHA supplements have become popular in recent years.

Supplementation may be useful for people with high cholesterol, heart disease, and numerous other conditions. It may also be beneficial for pregnant and breastfeeding women and in infant formula.

How Does It Work?

DHA is an essential fatty acid, which means that humans must obtain it from the diet. This product is thought to work in a variety of different ways, such as:

• Inflammation -- DHA seems to decrease inflammation in the body by suppressing a specific enzyme (COX-2) and inflammatory chemicals, such as interleukin-1 (IL-1) and tumor necrosis factor (TNF).
• Triglycerides -- DHA lowers triglyceride levels by several different mechanisms.
• Blood clotting -- DHA decreases blood viscosity (in common terms, it "thins" the blood) and has effects on red blood cells that may decrease the risk of blood clots.
• Fetal and infant development -- DHA is important for the development of the brain and neurons.

These are just a few of the ways that researchers think this product may work for a variety of conditions. As more studies are done, more information will become available.


Is DHA Effective?

DHA, especially when combined with eicosapentaenoic acid (EPA), has been studied much more than most dietary supplements and seems to be effective for several uses. Some uses have more scientific evidence in their favor than others.


Are There Side Effects?

DHA can cause several side effects, such as:

• Nausea
• Gas
• Bruising
• Prolonged bleeding.

Safety Issues With DHA

Normal doses of DHA are probably safe for most people, although high doses can cause problems. Some people may be more likely to experience problems than others. Therefore, you should talk with your healthcare provider prior to taking it if you have:

• High blood pressure
• A bleeding disorder
• Any allergies, including allergies to foods (especially fish), dyes, or preservatives.

Also, let your healthcare provider know if you are:

• Pregnant or thinking of becoming pregnant (see DHA and Pregnancy)
• Breastfeeding (see DHA and Breastfeeding).

[guns01]

Re: New Insights on How DHA Inhibits Prostate Cancer

wow this stuff looks pretty interesting. i wonder if it impacts muscle growth at all

[Guest]

Re: New Insights on How DHA Inhibits Prostate Cancer

wow this stuff looks pretty interesting. i wonder if it impacts muscle growth at all

Being as how this is an Omega 3 fatty acid I would have to conclude that it helps muscle growth.Here's some facts on Omega 3's and body composition............


Freedom from disease and a sharper mind is all good and well, but what what about biomakers related to body composition? Results from studies on n-3 intake and insulin sensitivity are mixed. In summary, people with poor insulin sensitivity (obese) usually see an improvement with n-3, while lean subjects see no or only modest improvements. Keep in mind that "lean" in a clinical context is 15-20% body fat for males and around 25% body fat for females.


What about n-3 and fat loss? I have not seen a single study which shows that adding n-3 alone will generate fat loss in lean subjects, but overweight/obese subjects sometimes see a small - but clinically significant - effect of n-3 supplementation. There are some exceptions to this, i.e. some studies do show a clinically significant fat loss effect in lean subjects, but the sample size and diet design is extremely poor - such as in this widely cited study by Couet, et al.


In combination with exercise, n-3 has been shown to accelerate fat loss in a few studies, but once againthe effect is limited to obese subjects.


However, I'll note that it's a profound flaw to look at the effects of n-3 and fat loss in lean subjects and conclude that there is no benefit. Why? Because the effect of n-3 on fat metabolism and adipose tissue is not acute. It takes approximately 4-6 weeks of n-3 supplementation to change the fatty acid composition of the cell membrane, and controlled interventions on n-3 supplementation and fat loss have never been longer than 12 weeks in duration. In the case of Brilla, et al., who looked at fat loss in lean subjects, it was 10 weeks.


The implication of this is that the study, or studies, on n-3 intake and fat loss in lean subjects might be too short in duration to show a clinically significant effect. The n-3 supplements simply didn't "kick in", if you will, until the passing of several weeks. Furthermore, any greater weight loss, as a percentage of body weight, is always harder to spot in lean subjects in comparison to obese subjects, unless you have a large sample size (Brilla, et al., used only 8 subjects in the fish oil + exercise group).

In conclusion, there simply aren't any good trials on n-3 supplementation and their role in fat loss yet. Oh sure, there are studies looking at fish intake and so forth, but I'm talking controlled interventions without a bunch of variables (fish protein, outpatient trials with poor control, etc.).

[guns01]

Re: New Insights on How DHA Inhibits Prostate Cancer

nice fist. reason why i raised an eyebrow to it is that somethings that promote anti-inflamitory reactions in the body inhibit muscle growth to some degree. that's what got the hamster running on that question