thoughts on ghrp and joint repair

[Rocker44]

have any of you guys tried site injections to help repair a joint or tendon injury ?
and did it help ?

[TwisT]

Re: thoughts on ghrp and joint repair

IGF is king of joint repair, not GHRP

[6p6]

Months ago I was site injecting Ghrp-6 and my joints started really coming around (knee) that being said the results plateaued and didn't feel like it helped much after awhile...but while it lasted it was great!

[Rocker44]

Re: thoughts on ghrp and joint repair

IGF is king of joint repair, not GHRP

ya got a little more info for me twist ?

[Rocker44]

Re: thoughts on ghrp and joint repair

Months ago I was site injecting Ghrp-6 and my joints started really coming around (knee) that being said the results plateaued and didn't feel like it helped much after awhile...but while it lasted it was great!

i have some ghrp2 on hand i was thinking of giving it a shot. no pun intended
i need 8 weeks out of it lol. then i will have to way my options

[6p6]

G2 should gv you the same affect...

[Pittsburgh63]

Re: thoughts on ghrp and joint repair

IGF Des is the way to go to pin point specific areas. Shoot IM as close to the issue as possible. It can do some wonderful things.

[suprfast]

Re: thoughts on ghrp and joint repair

Oh my, might be giving this a try. Where about would you inject if you were trying to aid issues with knees?

[Pittsburgh63]

Re: thoughts on ghrp and joint repair

I would hit your vastus medialis (Tear drop quad).

[suprfast]

Re: thoughts on ghrp and joint repair

Happen to have any info on the joint repair and igf pitt? Love learning new stuff.

[Pittsburgh63]

Re: thoughts on ghrp and joint repair

Happen to have any info on the joint repair and igf pitt? Love learning new stuff.

I do somewhere.. gotta dig a little, but I'll find something for you.

[Pittsburgh63]

Re: thoughts on ghrp and joint repair

Linda A. Dahlgren1, Marjolein C. H. van der Meulen2, John E. A. Bertram3, Greg S. Starrak1, Alan J. Nixon1,*Article first published online: 1 JAN 2006

DOI: 10.1016/S0736-0266(02)00009-8

Copyright © 2002 Orthopaedic Research Society


Abstract
Flexor tendinitis is a common and debilitating injury of elite and recreational athletes. Healing may be improved through intratendinous injection of insulin-like growth factor-I (IGF-I), which has been shown in vitro to stimulate mitogenesis and enhance tendon matrix production. This study investigated the effects of intratendinous injection of IGF-I on tendon healing in an equine model of flexor tendinitis. Collagenase-induced lesions were created in the tensile region of the flexor digitorum superficialis tendon of both forelimbs of eight horses. Treated tendons were injected with 2 μg rhIGF-I intralesionally every other day for 10 injections, while controls received 0.9% NaCl. Tendon fiber deposition and organization were evaluated serially using ultrasonography throughout the 8 week trial period. Following euthanasia, the tendons were harvested and DNA, hydroxyproline, and glycosaminoglycan content determined, mechanical strength and stiffness evaluated, gene expression and spatial arrangement of collagen types I and III assessed by northern blot and in situ hybridization, and tendon fiber architecture assessed by polarized light microscopy. Local soft tissue swelling was reduced in the IGF-I treated limbs. Similarly, lesion size in IGF-I treated tendons was smaller 3 and 4 weeks after initiation of treatment. Cell proliferation and collagen content of the IGF-I treated tendons were increased compared to controls. Mechanically, IGF-I treated tendons showed a trend toward increased stiffness compared to saline treated controls. Considered together with the decreased soft tissue swelling and improved sonographic healing, these data support the potential use of intralesional IGF-I for treatment of debilitating tendon injuries.

[Pittsburgh63]

Re: thoughts on ghrp and joint repair

Here's a quick abstract that I had saved on my laptop.. I think most of my stuff is saved on my wifes computer. I'll check later on and see what I have.

[suprfast]

Re: thoughts on ghrp and joint repair

Holy sweet mother...just saw the price on IGF. No problem though, if it works it will be worth every penny.

Says it can be diluted in either water or acid. Assuming that BAC water is still fine?
What is the normal dosage application of IGF DES for the joint repair application?

Thanks again for your time Pitt(and EZ).

[Pittsburgh63]

Re: thoughts on ghrp and joint repair

IGF should be recon'd with .6% AA solution. It'll degrade within days when recon'd with BAC. Dose ranges anywhere from 50-80mcg's on average.. I like IGF at 100mcg's personally. Start low and see how you respond.. then slowly work your way up. I'll shoot you a PM that may save you a few bucks on IGF.