antacids vs. lactic acid

[AS4life]

i've been trying to find out if what i heard was true, that antacids such as, tum, rolaids, etc... actually control lactic acid build-up, i've gone to a few sites to research but i haven't found anything out.
i love to know that it does, i'd never stop working out.

:2gunsfiri :2gunsfiri

[Governor]

no chance.

[morebeefplease]

antacids and lactic acid have nothing do with each other.

[Starr]

That is the most disgusting avatar, morebeef!

[morebeefplease]

lactic acid is a by-product of the tears in muscle fibers after working out. your body's own nutrient transport systems are want get rid of the build up.

[morebeefplease]

Originally posted by Starr
That is the most disgusting avatar, morebeef!

i know, but it is pudgy's fault, he said i couldn't have the hot chick that was originally my avatar.

[Starr]

I know, I had a great arse as mine for a while, also compliments of Pudgy, but I changed it. Maybe it's time to go back to it...

[morebeefplease]

maybe you should

[nox]

Depends on the antiacid. Sodium Bicarbonate (baking soda) is the choice here. It is an antiacid, but not found in TUMS and rolaids.

You can also use citrate as a buffer, I've heard it works better than bicarb, but haven't read the study. There is thread over at CEM called "metabolic acidosis" which overviews this.

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J Am Vet Med Assoc 1986 Mar 15;188(6):602-7

Dietary sodium bicarbonate as a treatment for exertional rhabdomyolysis in a horse.

Robb EJ, Kronfeld DS.

A 3-year-old mare repeatedly had clinical signs of rhabdomyolysis on mild exertion. Serum creatine kinase and aspartate transaminase activities were high at rest. Responses to dietary sodium bicarbonate were tested through 7 alternating periods of supplementation of a basal ration of timothy hay and oats. Physical signs; venous blood pH and gases; blood glucose and lactate; serum electrolytes, enzymes, and creatinine; and urine pH were monitored before and after exercise. Dietary sodium bicarbonate raised resting venous blood pH and bicarbonate slightly and significantly increased urine pH from pH 7.46 to 8.2 (P less than 0.001). An exercise test included 5 minutes at the walk followed by 20 minutes at the trot. The exercise induced gait stiffness, muscle fasciculations, and muscle induration when the diet was not supplemented, but not when it was supplemented with sodium bicarbonate. Myoglobin was present in 16 of 21 urine samples after exercise during nonsupplemented periods, but only in 3 of 28 urine samples during supplemented periods (P less than 0.0001). Bicarbonate supplementation significantly decreased the responses of blood lactic acid, serum creatine kinase, and aspartate transaminase to exercise. Supplementation of the diet was associated with higher venous blood pH and bicarbonate ion concentrations throughout exercise. Dietary sodium bicarbonate apparently mitigated or prevented physical, chemical, and enzymatic characteristics of exertional rhabdomyolysis in this mare, possibly through its enhancement of buffering capacity in muscle tissue fluids.

[bulldog_10]

It is very doubtful that lactic acid causes muscle fatigue...

[smalls]

Actually, morebeefplease, lactic acid is a waste product of glycolysis-fermentation and the use of pyruvate. But either way.

[nox]

Originally posted by bulldog_10
It is very doubtful that lactic acid causes muscle fatigue...

elaborate please.

[bulldog_10]

Originally posted by nox
elaborate please.

The idea that lactic acid causes muscle fatigue is an old one...the recent data suggests that muscle fatigue is linked more to inorganic phosphate accumulation from the breakdown of ATP.

[MYRICK]

Originally posted by bulldog_10
The idea that lactic acid causes muscle fatigue is an old one...the recent data suggests that muscle fatigue is linked more to inorganic phosphate accumulation from the breakdown of ATP.

whats ur point is this ur theory?

[bulldog_10]

Originally posted by MYRICK
whats ur point is this ur theory?

What's my point? My point is that lactic acid does not cause muscle fatigue, so why try to combat it?

And no, it's not my theory. Like I said, the latest data suggests that fatigue is linked to inorganic phosphate from the breakdown of ATP.

Want more details? Here you go:

Decrased pH doesn't slow glycolysis in vivo, only in biopsy samples

In persons with McArdle's syndrome and PFK (phosphofructo kinase) deficiencies, there is rapid muscle fatigue even though their muscles do not make lactic acid or have lowered pH in their muscles.

There is a poor correlation between decrease in muscle acidity and increased force during recovery from fatigue. So as you muscle gets less acidic, your muscle doesn't get stronger.

Little or no impact of decreased pH on force development during recent "skinned fiber" studies at physiological temperatures. A decrease in pH was found to negatively impact a muscle force development at cooler temps in older studies, because they needed to keep the muscle cool in order to preserve it.

On the other hand:

increased inorganic phosphate in the muscle has been shown to decrease calcium release from the sarcoplasmic reticulum, which results in decreased force production.

Increased inorganic phosphate has been shown to decrease calcium induced force production by actin-myosin cross bridges, even when the muscle fiber is bathed in calcium.

increased inorganic phosphate also decreases the rate at which calcium is taken back into the SR, which leads to slower muscle relaxation rate.

So like I said, combatting lactic acid build-up shouldn't be a priority.