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Being Suicide Inhibitors, what does the body do with the 'permanently binded' estrogen? I figure it must be handled somehow. ADex leaves a rebound effect... what are the post usage effects of these?
There is some info on Formeron in the BlackLionForum. people love it! ASk Brundel isf you have any questions about it
Thanx Baby... I totally forgot about his forum. I suppose I could of asked this in there. I do plan on getting some just curious as to how the body metabolizes the estro after it;s been binded.
To be totally honest Im not 100% certain how the body eliminates the permanently bound estrogen.
I do know 100% that Formeron is not liver toxic to any degree. Ill look into it and see if I can find an answer for us.
I do know that with Formeron and aromasin there is 0 potential for an estrogenic rebound.
This makes it ideal for our purposes.
Understand that AI's were not intended for our purposes but instead were intended to combat estro driven cancers.
For our purpose, suicidal AI's are a must for this reason:
In men, estrogen is created primarily via an enzymatic conversion.... testosterone>>>>AROMATASE>>>>estrogen
So, when estrogen is low the body makes more testosterone so it can be used to make more estrogen. Does this make sense?
Ok...so...its common sense then that if, post cycle, you get an estro rebound your PCT will fail miserably.
So on cycle we want to manage estro using a suicidal ai.
Then in PCT we want to also employ a suicidal AI to bottom out estrogen.
This way when PCT is over and the body begins to seek homeostasis it will start in a favorable state which is.....
Abnormally low estro and abnormally high test.
The estro will rise a bit and the test will drop a bit and we will wind up perfectly where we want to be.
After a little more research, it seems I mis-spoke when I said it binds to estrogen. In fact it binds to the aromatase enzyme.
Still I haven't found out what happens to the terminally bound enzyme. I'll keep looking as well.
Yeah, me too. The most I've found is this link that explains in great detail the binding process but not how the body handles the permanently bound enzyme.
This link was given to me on another board. Molecular characterization of aromatase
It mus be reabsorbed or passed out of the system somehow - Lymphatic system maybe?
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