Bromocriptine interacts with Zyrtec-D 12h tab ???

[DannyM]

I was planning on using Tren on my next cycle. My allergy medicine was switched to Zyrtec-D 12 hour tabs. I am reading the paper that comes in the box and it says

"DO NOT TAKE THIS MEDICINE fi you are also taking furazolidone or monoamine oxidase inhibitors (MOAI's), or if you allergic to hydroxyzine.ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking bromocriptine, guanethidine, guanafrel, urinary alkalyzers, methyldopa, or tricylic antidepressents."

Does this mean that I shouldnt take Tren because it requires Bromo to combat possibe sides ?

[DannyM]

ok, maybe no one esle takes Zyrtec-D 12 hour tabs.

I'm wondering how "safe" it would be to take bromo since the allergy medicine I take says what is in red up above.

How good or bad of an idea is it to use tren with out any bromo on hand? I've never done tren before so I really do not know how my body would react to Fina progestin.

I was planning on EQL Pro/Fina 1cc EOD.

[superchicken]

more than likely you wont get gyno, but its possible. thats why people take bromo to reduce the possibility. but tren is so fast acting that if you did start to get gyno just stop the tren the gyno wont have progressed very far at all. youll be fine. just stop asap if you see signs of it though. def dont mix meds if it sais not to.

and of course higher doses of tren increase your risk, maybe start a bit lower and ramp it up to test your tolerance to tren since its your first time if you wanna play it extra safe.

[DannyM]

thanks superchicken.

[nox]

Wow, great question. Its either due to addiction probability or dopamine overload.

You've got your Zyrtec which is an H1 (histamine) inhibitor. H1 inhibitors have been shown to activate dopamine receptors in the brain (1). Dopamine receptor activiation is known to produce dependence. Things such as cocaine and amphetamines are very good at activating dopamine receptors (some steroids too).
But I think the warning is just there out of theory since Zyrtec doesn't cross the blood-brain barrier.(2)
The other part is pseudoephedrine - a relative to amphetamine - which activates the same Dopamine receptor. (3)
And you're throwing Bromo into the mix which raises dopamine levels even more, but to my knowledge has no addictive properties.
This all adds up to a highly addictive situation, an overload probably resulting in a heart attack - or nothing at all.
I think you'll be fine, unless you're extremely sensitive. But I'm not here to think for you.

(1) Neuropharmacology 2001 Mar;40(4):624-33

Dopaminergic effects of histamine administration in the nucleus accumbens and the impact of H1-receptor blockade.

Galosi R, Lenard L, Knoche A, Haas H, Huston JP, Schwarting RK.

(2) Drug Metab Dispos 2003 Mar;31(3):312-8

P-glycoprotein limits the brain penetration of nonsedating but not sedating H1-antagonists.

Chen C, Hanson E, Watson JW, Lee JS.

(3) Neuropharmacology 1999 Sep;38(9):1381-7

Pseudoephedrine, a sympathomimetic agent, induces Fos-like immunoreactivity in rat nucleus accumbens and striatum.

Kumarnsit E, Harnyuttanakorn P, Meksuriyen D, Govitrapong P, Baldwin BA, Kotchabhakdi N, Casalotti SO

[Billy_Bathgate]

great post nox

[DannyM]

I'm probably going to do a tren/prop/winny cycle. It will be my next one or the cycle after that. I'm going to get bromo and keep it on hand just in case. I am going to take Vitex daily. If prog gyno appears then I'll stop the tren and stop taking my allergy medicine and take the bromo along with vitex until prog gyno symptoms go away.

I can control test gyno/estrogen with 25mg aromasin eod and nolvadex 10mg ed. I will use aromasin and nolvadex to control estrogen so if gyno appears with the tren/prop/winny then I know its the tren prog gyno.

Hopefully using the winny and vitex daily along with the prop/tren will prevent me from having to go off the allergy meds and start using bromo.

Thanks.