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1. HIGH doses work better due to shbg
2. insulin may help lower shgb
3. switching gear/dosages may help shgb as well
4. shgb is perhaps the reason why first cycles are the best cycles and are not go from there on after.
very interesting. i just dont think SHBG plays such a huge role that it will cost you much in gains. of course utilizing this knowledge coupled with other minor "gain" factors will equate in size for sure.
i have taken proviron for a long time now because it to binds to shbg and lowers estrogen.
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