Arimidex vs. Nolvadex controversy---Nolvadex 20mg every 4 days....Who does this?

[The_CR0W]

I originally planned on using Arimidex at .25mg EOD or ED during my Var(40mg/day for 8 wks), Sust (500mg/week for 10 wks) & Deca (400mg/week for 8 wks)cycle, however after doing further research I choosing to go with Nolvadex. I was told to use only Nolvadex at early symptoms of Gyno, however, would it be ok to go ahead and throw a 20mg tab every 3 or 4 days just to be safe? I know Nolvadex is somewhat liver toxic, but I am taking alot of precautions for my liver and feel a 20mg tab every 3 or 4 days would work well and wouldn't hinder my gains as opposed to taking one everday.

Reasons why I am going with Nolva over Arimidex:

1) Nolvadex doesn't totally block esterogen(works as a estrogen receptor atangoist) and I think my overall gains with using Nolva would be better than if I went with arimidex because some estrogen is good during a cycle most since it heavily promotes strength and gains as well (increases GH, upgrades the androgen receptor, improves glucose utilization).

2) Scared to death of cholestorol also.....arimidex may have a profound impact on HDL to LDL ratio's in my cholesterol profile.

What do you guys think??

[The_CR0W]

I understanding what your saying--use it sparingly when your feeling the typical characteristics(itchy nipples, soreness)of premature gyno. However, would using 20mg every 3 or 4 days have a considerable impact on my gains...Its always better to be safe than sorry right?

[Mudge]

It can affect your eyes anyway, I prefer arimidex. Billy Bathgate runs nolva though.

[Pheedno]

Nolvadex has been seen to cause ocular damage after prolonged use(5+ yrs)

Now, you don't want to take Nolva every 4-5 days becasue the 1. it would take you a couple of months to reach steady state plasma levels. 2. Half life is 5-7 so EOD would be needed to at least keep a consistant level.
Rule of thumb, it takes about 5x the half life to reach steady state blood levels. So taking it every 4-5 days would put your time frame at about 90 days.

Nolva also lowers IGF by considerable amounts. I'll pull a study on that from pubmed if you like.

I personally run .5mg of L-dex + 10mg of Nolva along side for it's SERM benefits. I figure the lipid benefit outweighs the IGF negative(and at 10mgED, IGF won't be hindered that much)

[INTIMID8OR]

I think you'd get better results saving the nolva for post cycle therapy with clomid and running proviron in the cycle....Just my opinion... take care...

[Mudge]

Honestly, I seem to get some mild strobing effects from nolvadex from time to time early in the AM, I dont have that issue without it. Supposedly it is alot less than clomid, but yes it does affect ocular yada yada in some people.

[The_CR0W]

Thanks for the research studies....

I'm very hesistant in using more than .25 mg of A-dex per day. I want to go with .25mg EOD.


So that brings me to my next question, would would be more of an effective measure to prevent the formation of gyno and not raise hell on my Lipid Profile.

A) .25mg A-dex EOD
B) 10mg of Nolva EOD

please give me your input on that...

BTW this board is alot more helpful than other boards, I've been noticing.

[The_CR0W]

Originally posted by Crankin'steiN
If your that worried about gyno and water retention, and you are going to run an anti-e throughout, then why not just run Nolva at 10mg throughout.

It won't hinder any gains, except maybe a bit of water....... and you should be pretty safe from gyno and such....

Yes but wouldn't .25mg EOD or ED of A-dex be more effective for such a thing rather than 10mg of Nolva ed?