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Saw this on another site. Its like $29 for 120 capsules. Seems pretty cheap and all the reviews on it seem unbelieveable. People saying they are eating junk and still loosing fat. Anyone heard of this stuff or know if it works?
Sesapure is the highest purity extract of Sesame lignans available. The high levels of two chemicals (known as : Sesamin and Episesamin) powerfully activate and improve the metabolism of fat and sugar (called PPAR-alpha agonism). Research indicates these 2 chemicals:
• Speed up Fat loss
• Reduce Fat gain even when eating extra calories. If you are bulking or just plain overeating, it can mean more muscle and less fat.
• Improve insulin sensitivity and better sugar metabolism
• Increase mitochondrial activity inside your cells, and therefore provide more energy production
• Protect the liver
• Decrease triglycerides
• Provides anti-inflammatory actions, protecting the brain, blood vessels and body from damaging inflammation
• Lower LDL (bad) cholesterol
• Raise HDL (good) cholesterol
• Increase vitamin E levels. Studies indicate that vitamin E not only protects the body from oxidation that can cause premature aging, but
also can elevate and/or restore testosterone levels
Sesapure will help you get or stay lean while providing significant health benefits.
What are PPAR's?
PPAR's (or Peroxisome Proliferator Activated Receptors), are receptors in the nucleus of your cells. These receptors help control fat metabolism, energy balance, and glucose metabolism. Many pharmaceutical companies are working to develop PPAR based drugs, since they have huge implications with respect to obesity, liver disease, hypertension, cholesterol and diabetes.
How does Sesamin increase fat loss?
Sesamin and episesamin are chemicals that strongly activate PPAR-alpha, and increase mitochondrial and peroxisome activity. Basically this increases fatty acid metabolism significantly. Also, Sesamin increases the expression of a mitochondrial enzyme known as carnitine palmitoyl transferase. Carnitine palmitoyl tranferase is an enyme that shuttles fatty acids to the mitochondria, making more fatty acids available for use as energy. When you take Sesamin it can be like putting your fat on a one-way bus to the fat furnace. To top it off Sesamins activation of PPAR-alpha increases the production of "uncoupling proteins" (UCP's). Uncoupling proteins are kind of like DNP, except legal and safe. The amount of UCP's that you produce is one of the main factors in what your basal metabolism is. Electrons are transferred in the inner membrane of the mitochondria, and produce ATP in exchange . When this electron transport chain is "uncoupled" you burn energy (mostly fat) oxidatively (with oxygen), at an accelerated rate. So basically Sesamin and episesamin shift your metabolism considerably more in favor of utilizing fat, instead of storing it.
How is this going to help me when Bulking?
SesaPure will decrease your ability to store fat. Sesamin and episesamin reduce the production of the lipogenic enzymes FAS (fatty acid synthetase), acetyl-CoA carboxylase, ATP-citrate lyase, glucose-6-phosphate dehydrogenase and sterol regulatory element binding protein-1 (SREBP-1). Basically it reduces your bodies ability to store fats.
What will SesaPure do for my liver?
Sesamin and episesamin have been shown to inhibit fatty vacuole formation in the liver that can occur with alcohol use/abuse. They do this by increasing liver fatty acid oxidation as well as by helping to efficiently metabolise alcohol.
Sesamin and episesamin have been shown to raise aldehyde dehydrogenase levels by more than 3 fold. When alcohol is consumed, it enters cells and is broken down into a toxic compound known as acetaldehyde. An enzyme called aldehyde dehydrogenase 2 (ALDH2) converts the acetaldehyde into acetic acid, which is non-toxic and can be readily used by your body to provide energy. Basically its helps your body to "safely" metabolize alcohol. This is not to encourage alcohol use/abuse, but simply an example of how Sesamax helps protect your liver by making it more efficient.
Sesapure is the highest purity extract of Sesame lignans available. The high levels of two chemicals (known as : Sesamin and Episesamin) powerfully activate and improve the metabolism of fat and sugar (called PPAR-alpha agonism). Research indicates these 2 chemicals:
• Speed up Fat loss
• Reduce Fat gain even when eating extra calories. If you are bulking or just plain overeating, it can mean more muscle and less fat.
• Improve insulin sensitivity and better sugar metabolism
• Increase mitochondrial activity inside your cells, and therefore provide more energy production
• Protect the liver
• Decrease triglycerides
• Provides anti-inflammatory actions, protecting the brain, blood vessels and body from damaging inflammation
• Lower LDL (bad) cholesterol
• Raise HDL (good) cholesterol
• Increase vitamin E levels. Studies indicate that vitamin E not only protects the body from oxidation that can cause premature aging, but
also can elevate and/or restore testosterone levels
Sesapure will help you get or stay lean while providing significant health benefits.
What are PPAR's?
PPAR's (or Peroxisome Proliferator Activated Receptors), are receptors in the nucleus of your cells. These receptors help control fat metabolism, energy balance, and glucose metabolism. Many pharmaceutical companies are working to develop PPAR based drugs, since they have huge implications with respect to obesity, liver disease, hypertension, cholesterol and diabetes.
How does Sesamin increase fat loss?
Sesamin and episesamin are chemicals that strongly activate PPAR-alpha, and increase mitochondrial and peroxisome activity. Basically this increases fatty acid metabolism significantly. Also, Sesamin increases the expression of a mitochondrial enzyme known as carnitine palmitoyl transferase. Carnitine palmitoyl tranferase is an enyme that shuttles fatty acids to the mitochondria, making more fatty acids available for use as energy. When you take Sesamin it can be like putting your fat on a one-way bus to the fat furnace. To top it off Sesamins activation of PPAR-alpha increases the production of "uncoupling proteins" (UCP's). Uncoupling proteins are kind of like DNP, except legal and safe. The amount of UCP's that you produce is one of the main factors in what your basal metabolism is. Electrons are transferred in the inner membrane of the mitochondria, and produce ATP in exchange . When this electron transport chain is "uncoupled" you burn energy (mostly fat) oxidatively (with oxygen), at an accelerated rate. So basically Sesamin and episesamin shift your metabolism considerably more in favor of utilizing fat, instead of storing it.
How is this going to help me when Bulking?
SesaPure will decrease your ability to store fat. Sesamin and episesamin reduce the production of the lipogenic enzymes FAS (fatty acid synthetase), acetyl-CoA carboxylase, ATP-citrate lyase, glucose-6-phosphate dehydrogenase and sterol regulatory element binding protein-1 (SREBP-1). Basically it reduces your bodies ability to store fats.
What will SesaPure do for my liver?
Sesamin and episesamin have been shown to inhibit fatty vacuole formation in the liver that can occur with alcohol use/abuse. They do this by increasing liver fatty acid oxidation as well as by helping to efficiently metabolise alcohol.
Sesamin and episesamin have been shown to raise aldehyde dehydrogenase levels by more than 3 fold. When alcohol is consumed, it enters cells and is broken down into a toxic compound known as acetaldehyde. An enzyme called aldehyde dehydrogenase 2 (ALDH2) converts the acetaldehyde into acetic acid, which is non-toxic and can be readily used by your body to provide energy. Basically its helps your body to "safely" metabolize alcohol. This is not to encourage alcohol use/abuse, but simply an example of how Sesamax helps protect your liver by making it more efficient.
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