TweetYou can do sub q or im. Most do sub q, 31g is fine I use a 29g 1/2" slim pin. I am not sure there really is a wrong way to run it aside from using too high a dose in one shot. It's all personal preference. You can do 250 2x a week thru out, I've seen good results from people using it at the end at 500iu/day for 20-30days with nolva protocol. I personally have always ran it the last 5 weeks of my cycle leading me into post at 500ius 2x a week. Then a standard nolva post with clomid, torm, or just nolva.