Reply With QuoteTweetI'm currently researching leukotriene modifiers to see if inhibiting the production will limit vascular side effects from tren- shortness of breath, "cough", etc.
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Tren- Fat burning and "fina cough" both from prostaglandin metabolization
TweetPosted on AR & IBB as well-
It's been widely disussed of Trens fat burning properties through rises in IGF and Prostaglandins. While IGF is a fairly well known substance in the bodybuilding world today, prostaglandins are fairly unknown in terms of formation and roles in the body.
So below, a brief dicription of prostoglandins and their role in fat burning, "fina cough", and why a person going through Tren administration can experience it's fat burning effects without the dreaded "Cough"
The term prostaglandin comes from the word-Prostate. The first prostoglandins were first dicovered in semen about the mid 1930's and it was thought that prostaglandins were made from the prostate. Since this time, it has been dicovered that most prostaglandins are not even constructed in the prostate.
Prostaglandins are made by two different pathways(Cyclooxygenase and Lipoxygenase), and considering prostaglandins are a group of about 20 lipid cells, they have contrary function; responsible for stimulating as well as alleviating inflammation(Inflammation stimulation is the rapid metabolism of them expelled through the bronchials), regulate blood flow to particular organs, control ion transport across membranes, modulate synaptic transmission, induce sleep, mediate lipid release, and regulate metabolism is various tissue.
Prostaglandins are synthesized from arachidonate(Lipoxygenase which catalyze the dioxygenation of polyunsaturated fatty acids) in the cell membrane by the action of phospholipase A2. Cyclooxygenase and lipoxygenase pathways, compete with one another to form prostaglandins(as well as thromboxane or leukotriene-leukotriene being a bronchial stimulator),
In the cyclooxygenase pathway, the prostaglandins D, E and F plus thromboxane and prostacyclin are made. Thromboxanes are made in platelets and cause constriction of vascular smooth muscle and platelet aggregation
Leukotrienes are made in leukocytes and macrophages via the lipoxygenase pathway. They are potent constrictors of the bronchial airways. They are also important in inflammation and hypersensitivity reactions as they increase vascular permeability.
Being that prostaglandins from either pathway, are still fatty acids of a group, they mediate lipid release and controll tissue metabolization, so fat burning is a luxerry of either pathway of formation. It's the pathway from which they are constructed that dictates "fina cough". As prostaglandins made from the Cyclooxygenase pathway dictate muscle constriction and platlet aggregation, and the Lipoxygenase pathway dictates bronchial constriction(the main form of expulsion)
Refs:
Cackatoo Press
Columbia Encyclopedia 6th Edition
Science Daily Magazine
"The tragedy of life is not found in failure but complacency. Not in you doing too much, but doing too little. Not in you living above your means, but below your capacity. Never failure but low aim, is life's greatest tragedy"- Benjamin Mayes
"The power of accurate observation is commonly called cynicism by those who have not got it"- George Bernard Shaw
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TweetI'm currently researching leukotriene modifiers to see if inhibiting the production will limit vascular side effects from tren- shortness of breath, "cough", etc.
"The tragedy of life is not found in failure but complacency. Not in you doing too much, but doing too little. Not in you living above your means, but below your capacity. Never failure but low aim, is life's greatest tragedy"- Benjamin Mayes
"The power of accurate observation is commonly called cynicism by those who have not got it"- George Bernard Shaw
Tweetvery nice post bro
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Tweetnandrolone is shown to increase prostaglandin production.....tren is similar to deca and anyone who knows about these powerful hormones (prostaglandins) knows they burn fat..... pgf2a
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TweetEvery exogenous hormone increases prostaglandin production with release, Hormones with strong aspects of androgenocity(in repects to binding affinity) have the greatest effect on this.Originally posted by prophet
nandrolone is shown to increase prostaglandin production.....tren is similar to deca and anyone who knows about these powerful hormones (prostaglandins) knows they burn fat..... pgf2a
And prostaglandins are not hormones. They are a group of about 20 lipids that are modified fatty acids attached to a 5 membered ring.
"The tragedy of life is not found in failure but complacency. Not in you doing too much, but doing too little. Not in you living above your means, but below your capacity. Never failure but low aim, is life's greatest tragedy"- Benjamin Mayes
"The power of accurate observation is commonly called cynicism by those who have not got it"- George Bernard Shaw
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TweetOriginally posted by Pheedno
And prostaglandins are not hormones. They are a group of about 20 lipids that are modified fatty acids attached to a 5 membered ring.
LOL....you sound like you "think" you know what you are taking about. but they are very similar to hormones. by definition they are localized vs systematical.
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Tweetnice read, i wish i had more knowledge so i could understand it...
currently cutting:
wt: 210lbs
ht: 5'11"
bf%: 11%
current cycle:
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GU... RIP fallen brother...
Tweetnice read. bump for more info.
Tweeti was wondering why the tren makes you so hard and lean so quickly. i had it simplified to me "muscle gain without water retention" i did some research on the fina cough and came up with notta. so thanks for the great post guys
Re: Tren- Fat burning and "fina cough" both from prostaglandin metabolization
Tweetsounds good.....but why is it that i (and other users have reported also) only experience the "fina cough" from the vetinary implant conversion??..ive used pharmaceutical Tren and have not had the cough..Doesnt make sense....and also when you administer a shot...sometimes you gety the cough that split second upon injenction..I dont think that all that chemical reaction and pathway formation can occur within a split second of administration of a shot....Originally posted by Pheedno
Posted on AR & IBB as well-
Being that prostaglandins from either pathway, are still fatty acids of a group, they mediate lipid release and controll tissue metabolization, so fat burning is a luxerry of either pathway of formation. It's the pathway from which they are constructed that dictates "fina cough". As prostaglandins made from the Cyclooxygenase pathway dictate muscle constriction and platlet aggregation, and the Lipoxygenase pathway dictates bronchial constriction(the main form of expulsion)
Refs:
Cackatoo Press
Columbia Encyclopedia 6th Edition
Science Daily Magazine
Established Member
TweetWell, the cough is possible with pharm product, just as it's possible with testosterone.
This was sort of a work in prgress and firther research has revealed that arachidonate synthesization cannot be taken on so quickly. The total theory is not debunk though as I've seen exogenous LE2 be administered, metabolised, and transformed with a half life of 7 minutes
"The tragedy of life is not found in failure but complacency. Not in you doing too much, but doing too little. Not in you living above your means, but below your capacity. Never failure but low aim, is life's greatest tragedy"- Benjamin Mayes
"The power of accurate observation is commonly called cynicism by those who have not got it"- George Bernard Shaw
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TweetConversion chems an such passin' from capillaries to alveoli........
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Tweetgood post...hard to believe how u can cough almost instantly after injection...like as soon as i pull the pin out i get short of breath for a minute
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Tweetthis was a good read...but before, i though that drugs like deca and fina, which causes a rise in prostaglandins were to be AVOIDED for fat loss...from what ive took to knowledge from my peers was that deca or fina might give a negative effect of actually accumulating fat...that's why some threads recommended taking bromo for puffy nip syndrome due to the rise in prostaglandins...can someone clarify this matter...taking fina is great in burning fat in my experiences, like no other drug...the only downside is the effect it has on me sexually even with small doses of test....so can someone draw a conclusion where this thread places that prostaglandins help burning fat, whereas what ive read in past posts it might actually help in accumulating fat?
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