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    Thread: SARMS 101 MK 677 Ibutamoren

    1. #1
      joe1313's Avatar
      joe1313 is offline Platinum
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      Thumbs up SARMS 101 MK 677 Ibutamoren



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      • SARMS 101 MK 677 Ibutamoren
      • SARMS 101 MK 677 Ibutamoren
      • SARMS 101 MK 677 Ibutamoren
      • SARMS 101 MK 677 Ibutamoren
      SARMS 101 MK 677 Ibutamoren
      MK677.pngMK-677-2.pngMK-677-3.jpeg

      Note MK 677 is not a SARM

      Chemical Name: C27H36N4O5S
      Other Name(s): Ibutamoren Mesylate, MK-0677, L-163,191, L163191, Nutrobal, Oratrope, Crescendo
      CAS: 159752-10-0
      Powder Purity: >99% HPLC
      Solubility: Water, DMSO, Ethanol, Propylene Glycol
      Molar Mass: 624.77 g/mol
      Chemical Formula: C27H36N4O5S
      Short term storage (weeks): 0-4 C under dry condition
      Long Term Storage (months): -20 C under dry condition
      Shelf Life: At least 4 years if properly stored
      Melting Point: 156 158 C
      Appearance: Off-white to beige fine powder, hygroscopic, acrid odor, acrid metallic taste
      Biological half-life: 24 hours
      Suggested Intake: 25-50mgs/day, dependent on goal


      MK-677 (Ibutamoren) is a growth hormone secretagogue, which mimics the growth hormone. It also increases insulin-like growth factor 1 (IGF-1). Researchers have found MK-677 to help build muscle, reduce muscle wasting, increase bone density, and reverse aging.



      Growth hormone pulse intensity can be increased through 4 possible mechanisms:

      Increasing GHRH (growth hormone releasing hormone) release.
      Amplifying GHRH signaling in somatotrophs of the anterior pituitary gland.
      Reducing somatostatin release (somatostatin turns off GH release).
      Inhibiting of somatostatin receptor signaling.


      Mk-677 was found to work through all 4 of these mechanisms. After ingestion, Growth Hormone (GH) was shown to increase dose dependently, at doses starting at 5 milligrams (mgs) a day.


      How it works: MK-677 increases growth hormone levels and binding to one of the ghrelin receptors (GHSR) in the brain. Activated GHSR stimulates growth hormone release. GHSR is found in brain regions that control appetite, pleasure, mood, biological rhythms, memory, and cognition. As a result, researcher have found that MK-677 can also affect these functions.


      Intake: Due to its half-life, the suggested daily dose can be taken all at once
      Recommended Cycle: 12-16 Weeks is optimal
      Post Cycle Therapy (PCT): Not required


      Side effects: Some of the usual side effects that go with elevated GH levels such as numb hands, some lethargy, as well as slight increased appetite have been reported with the use of Mk-677. Interestingly, during prolonged administration both IGF-1 and GH were increased with no increase in cortisol.


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    2. #2
      guns01's Avatar
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      Default Re: SARMS 101 MK 677 Ibutamoren

      i saw labs from someone done after 60 days with mk677 and his igf levels almost tripled. they were low to begin with but it cranked them up big time
      TGBSupplements REP

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      Use code 'Baby1' for $5 off your order

    3. #3
      jipped genes's Avatar
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      Default Re: SARMS 101 MK 677 Ibutamoren

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      I love the stuff. I cannot afford GH, but I can afford MK677
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