I prefer IM injections. This is based on pharmacology and clinical observation. First, many people report pain, irritations, redness, nodules at the site of injection. There is also an adipose layer in virtually every SC site. Injection of a substance with pH lower than 7 (neutral) can cause these adverse effects. All water-based and alcohol-based injectible solutions are slightly acidic--some more than others. It is the low pH factor that causes the problem. oil-based injectibles are neutral or slightly basic and do not cause any of the adverse sides. to combat this problem, I have recommended injecting HGH into the quad muscle. Some people can achieve this with a 1/2" needle, some have to use a longer needle to get past the adipose layer and into the muscle.

The advantages of injecting IM is one--less discomfort and adverse effects, and two--a greater increase in IGF levels than injecting into SC tissue (adipose). You still get the same fat burning effects that you would injecting SC, but you also get greater IGF levels doing so. SC Injection does not allow the HGH to get into the bloodstream to raise IGF levels. The HGH stays localized in the adipose tissue, only providing fat-burning.

Some people can achieve this with a 1/2" needle, some have to use a longer needle to get past the adipose layer and into the muscle.

So depends on how far you need to go to muscle, you should be able to tell if its your