Tweetno this would be my 3rd shot.....I have only been on for a week in half, it will be 2 weeks come sunday...Hard to explain exactly where I injected at...on my quad..but when I stand up..I put my arms down and use my thumbs...to find the area..I have hit my quads the past 2 cycles...and have been perfect, all in the same area..kind of funny...because now I feel like I messed up or something..but never ever had a problem hitting my quads..