TweetSide note: I have used this and had great results with it. I always use it after a cycle to beat that depressed feeling I get.
Tweet5-HTP: Alternative for Depression
Author: Prion
Simple biochemistry to get every one up to speed: 5-hydroxytryptophan is a metobolic intermediate to seritonin. The amino acid L-tryptophan is converted to 5-HTP then to seritonin through the use of specific enzymes in the CNS, chromaffin cells of the gut, and enteric cells.
5-HTP has been show to be as effective as prozac in clinical studies with fewer side effect. The idea is by increasing the levels of 5-HTP the body will convert/metabolize the compound in to seretonin thus effecting mood.
Common doages of 5-HTP is 50mg three times a day after a two week trial the dose can be raised to 100mg three times daily. The maximum dosage being 900mg (extreme).
"The most common use for 5-HTP is to treat depression. Preliminary research has shown that 5-HTP may be as effective as antidepressants, with fewer and less severe side effects. In a six week research study, 63 people were given either 5-HTP (100 mg three times a day) or an antidepressant in the Prozac family (fluvoxamine, 50 mg three times a day). They were found to be equally beneficial."[1]
Like other antidepressants, 5-HTP can be used to treat the following conditions:
Insomnia - because serotonin is converted into melatonin, a compound essential for sleep
Migraine headache prevention - to decrease the frequency and severity of migraines
Fibromyalgia - to decrease symptoms of fibromyalgia
Weight loss - 5-HTP is believed to be involved in sending the brain the signal to stop eating
Contraindications to use are as follows: Pregnant or nursing women, people with liver or kidney disease, and children with down's syndrome. The following drugs are contraindicators as well:
Anti-depressant drugs
Monoamine oxidase inhibitors
Selective Serotonin Reuptake Inhibitors (SSRI's e.g., Prozac)
Tricyclic medications
Weight Loss medications (i.e., dextenfluramine)
Anti-parkinson medications (e.g., L-dopa, carbidopa)
Barbiturates and other tranquilizing drugs
Antihistamines and cold medications
Alcoholic beverages
Intravenous (illegal I.V.) drugs
Cancer chemotherapy or antibiotic medications
Pain medication Tramadol
----------------------------------------------------------------------------
References:
Serotonin a la carte: Supplementation with the serotonin precursor 5-hydroxytryptophan.
Pharmacol Ther. 2005 Jul 13; [Epub ahead of print]
PMID: 16023217 [PubMed - as supplied by publisher]
Safety of 5-hydroxy-L-tryptophan.
Toxicol Lett. 2004 Apr 15;150(1):111-22. Review.
PMID: 15068828 [PubMed - indexed for MEDLINE]
One on one. Can a supplement of 5-HTP help relieve my depression?
Mayo Clin Womens Healthsource. 2001 Jun;5(6):8. No abstract available.
Tryptophan and 5-hydroxytryptophan for depression.
Cochrane Database Syst Rev. 2002;(1):CD003198. Review.
"Better Things for Better Living...Through Chemistry." -DuPont
"...Indeed, there comes a time in every little slugger’s life when he's faced with the difficult decision of whether to shoot a needle into his butt and turn himself into the Incredible Hulk...or to take the higher road and pursue a career as a coal miner, but at least be able to have a few children before dying of black lung disease."
TweetSide note: I have used this and had great results with it. I always use it after a cycle to beat that depressed feeling I get.
"Better Things for Better Living...Through Chemistry." -DuPont
"...Indeed, there comes a time in every little slugger’s life when he's faced with the difficult decision of whether to shoot a needle into his butt and turn himself into the Incredible Hulk...or to take the higher road and pursue a career as a coal miner, but at least be able to have a few children before dying of black lung disease."
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TweetThey put it in some melatonin supplements to help you sleep.
TweetI have used it personally and it works wonders. Even if you don't have depression it will help with mood swings. I notice when I take it I just let stuff go easier. I don't dwell on stupid stuff that I have no control over and I don't explode as easily. Seritonin is the 'feel good' hormone and we could all use that from time to time.
Good post bro!
Tweetvery nice read bro
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Note: All of my advice and posts are merely for educational purposes I do not condone the use of steroids or any other illegal drugs. I am no doctor and my advice should be taken with a grain of salt, just like everyone else's hypothetical advice.
TweetThanks guys.
"Better Things for Better Living...Through Chemistry." -DuPont
"...Indeed, there comes a time in every little slugger’s life when he's faced with the difficult decision of whether to shoot a needle into his butt and turn himself into the Incredible Hulk...or to take the higher road and pursue a career as a coal miner, but at least be able to have a few children before dying of black lung disease."
TweetGood read, gonna try it!
Tweetjust bought some yesterday, 50mgs each. how much do you did you take bro? i took two a day for today and yesterday so far...
TweetI wouldnt take more than 100mg/day starting out. I take 50mg/day personally. If you feel the need to go up in dosage wait a week then bump it up. I know that the artical says 50mg/3xday but that may be hard to do considering it makes you drowsy. You should notice a good difference in approximatly 1-2 weeks. Let me know how it goes!
"Better Things for Better Living...Through Chemistry." -DuPont
"...Indeed, there comes a time in every little slugger’s life when he's faced with the difficult decision of whether to shoot a needle into his butt and turn himself into the Incredible Hulk...or to take the higher road and pursue a career as a coal miner, but at least be able to have a few children before dying of black lung disease."
TweetNice, I'll just drop it back to 50mgs a day then and see how it goes. I have a ton of stressful things going on right now so if it helps me, it's gotta be good! I'll keep ya posted for sure!