Preventing and Alleviating Progesterone Induced Gyno

[Cannons]

TweetIt seems that everyone is curious about the dreaded gyno caused by deca and tren and what they can do to prevent or get rid of progesterone induced gyno once it starts. One method is to cycle bromocriptine. It is made to reduce prolactin levels in the body which alleviates progesterone and prevents lactation (and or gyno in males case). However this comes with many negative side effects and its been proven that vitamin B6 is just as effective without the harsh side effects. Read the article below for a more indepth look at the comparisons, pros and cons.....

Originally posted on AR by Pheedno.


The following are excerpted from OB/GYN class notes:
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Suppression of Lactation:

When the mother chooses not to breast feed or the baby is lost, suppression of lactation may be required. Initially the breasts get engorged, however in the absence of suckling further milk production stops on its own. Firm support to the breasts is helpful in reducing the discomfort. Manual expression is not very helpful as it promotes further milk secretion. Estrogens in high doses can suppress lactation, however there are side effects and the risk of venous thrombosis, hence these are not recommended. Bromocryptine, a dopamine agonist, given 2.5 mg twice a day for 14 days can suppress lactation by producing a fall in prolactin levels. This therapy is expensive, has side effects and there may be rebound lactation once the drug is stopped. FDA no longer approves it. Pyridoxine – Vitamin B6, given 200 mg three times a day for 5-7 days is quite effective in suppressing lactation and the drug has no side effects.
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Got Wood? note : adding Bromo to your cycle only adds to the potential anabolic cascade, and potentially negative drug interactions. In medicine B6 is supposed to be as effective as Bromo. Plus vitamin B6 has few side effects.
Here are a few of many studies supporting the use of Vitamin B6 in reducing prolactin:
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J Clin Endocrinol Metab 1976 Mar;42(3):603-6


Effect of pyridoxine on human hypophyseal trophic hormone release: a possible stimulation of hypothalamic dopaminergic pathway.

Delitala G, Masala A, Alagna S, Devilla L.

A single dose of pyridoxine (300 mg iv) produced significant rises in peak levels of immunoreactive growth hormone GH and significant decrease of plasma prolactin PRL in 8 hospitalized healthy subjects. Serum glucose, luteinizing hormone LH, follicle stimulating hormone FSH and thyrotropin TSH were not altered significantly. In addition, in 5 acromegalic patients who were studied with both L-dopa and pyridoxine, inhibition of GH secretion followed either agent in a similar pattern. These data suggest a hypothalamic dopaminergic effect of pyridoxine.

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N Engl J Med 1982 Aug 12;307(7):444-5

Pyridoxine (B6) suppresses the rise in prolactin and increases the rise in growth hormone induced by exercise.

Moretti C, Fabbri A, Gnessi L, Bonifacio V, Fraioli F, Isidori A.

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Boll Soc Ital Biol Sper 1984 Feb 28;60(2):273-8

[Influence of administration of pyridoxine on circadian rhythm of plasma ACTH, cortisol prolactin and somatotropin in normal subjects]

[Article in Italian]

Barletta C, Sellini M, Bartoli A, Bigi C, Buzzetti R, Giovannini C.

The influence of vitamin B6 in a dosage of 300 mg X 2 in 24 hrs, on circadian rhythm of plasmatic ACTH, cortisol, prolactin and somatotropin have been studied in 10 normal women. After vitamin B6 24 hrs pattern of ACTH and cortisol is unchanged; prolactin levels are slightly lower, in a statistically unsignificant proportion the night peak of growth hormone is higher in a statistically significant proportion (p. 0.05). The effect of vitamin B6 is likely to me mediated by dopaminergic receptors at hypothalamic level as previous studies by other Authors appear to prove.

[SMILEY FACE]

Tweeti only get gyno when i do anadrol, i cando test as high as 1000 mg for 12 weeks and tren and deca, and will not get it, dunno why

[TSR1969]

Tweetbromo sucks, sides are way to bad cabergoline is great to get rid of deca/tren gyno

[Double]

Tweetslightly lower?? thats it???

[Cannons]

TweetThat was only after a 24 hr period. Thats why if you are taking Tren or Deca, you should take B6 (just like you would take nolvadex or arimidex or aromasin) throughout the cycle so its already built up in your system. I myself believe it works. A friend of mine was on 100mg of Tren ed and I had him taking 200mg of B6 ed. He started to get some gyno around week 9 so he bumped up the b6 to 600mg ed and within a week the symptoms were gone. Just my experience.

[macka]

Tweetgood info

[MIKE_XXL]

TweetI used Bromo and Tren still gave me lumps, the lumps reduced in size by 90% after i discontinues the Tren, i did not feel Bromo did much for me, i think i am just one of the very sensitive people to Progesteron induced Gyno, no tren for me...XXL