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    Thread: non toxic oral

    1. #1
      enrique's Avatar
      enrique
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      Question non toxic oral



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      I know the everyone refrains form using orals and for good cause but i read about this one and just wanted some feed back on it

      week 1-7 (8, 40mg caps of androil and 50mg primobolan tabs ed)
      pct nolva


      its not a cheap one!

    2. #2
      SMILEY FACE's Avatar
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      i hear that andriol is safe but dunno about primo tbs

    3. #3
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      ANDRIOL IS A WASTE IMO YEAH ITS SAFE BUT WHY USE IT YOU NEED A TON OF IT TO GET THE EFFECTS YOU WANT AND PRIMO TABS WELL IF YOU GOT THEM TELL US HOW THEY WENT BUT I SAY NO TO BOTH USE ANAVAR
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    4. #4
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      Andriol is a unique oral testosterone product, developed by the international drug firm Organon. One of the more recently developed anabolic steroids, Andriol first became available in the early 1980's. Andriol contains 40 mg of testosterone undecanoate, based in oil (oleic acid) and sealed inside a capsule. Subtracting the ester weight, this equates to a dosage of approximately 25 mg of raw testosterone per cap. The design of Andriol is quite different from that of most oral steroids. Drugs administered orally generally enter the blood stream through the liver. When a steroid compound is given this way without some form of structural protection, it will be quickly broken down during the "first pass". This process leaves very little steroid intact, basically deactivating the drug. Adding a methyl group (c-17 AA) to the structure is one way to protect it from this process, however stress is also placed on the liver as a result. In some instances this stress can lead to actual damage to liver tissues, so the designers of this steroid sought another way to protect the testosterone molecule. With Andriol, this was accomplished by making a form of testosterone that would be absorbed through the lymphatic system. This is due to its high fat solubility brought about by the ester, and its suspension in oil. Having the compound absorbed this way was thought to be very advantageous, as it allows the steroid to bypass the destructive first-pass through liver. This should permit the compound to enter the blood stream intact, without the need for a harsh chemical alteration. The ester breaks off once it is in circulation of course, yielding free active. In design Andriol appears to be that of a completely liver safe and orally active form of testosterone.



      ANDRIOL 40mg (Italy)
      On paper Andriol seems like an ideal oral testosterone product. Clean, safe and worlds apart from other oral testosterone derivatives like the crude methyltestosterone. But as we always hear in life, if it looks to good to be true, it probably is. And there are definitely some issues with Andriol. The first problem is that bioavailability, although clearly worlds apart from trying to take straight testosterone orally, is probably not significant next to c17-alpha alkylated orals. Athletes typically find that in doses of less than 240 mg per day (6 capsules) effects are generally not seen at all. 240 mg of testosterone ester daily, the primary male androgen, and only a meager effect. When doses go higher, maybe 8-10 capsules (320-400 mg) , new muscle growth is slight to moderate at best, but no incredible bulky gains are ever reported. Logic leads one to think that only a little testosterone is making its way into circulation. Testosterone is a powerful hormone no matter what the ester or form of administration. If it were active in the blood stream, the results would have to be pronounced. When one injects an oil based testosterone ester, a dosage of 400 mg per week is more than sufficient. 400 mg Andriol per day should be packing on an incredible amount of mass. Where does it all go?

      Individual problems with Andriol absorption may play into things here. Clearly there is little to be said except that this drug is unpredictable in its ability to be absorbed and utilized by the body. While one day you might be getting great absorption, perhaps the next day you are getting very little. Studies with men were no better than with women, where again Andriol was shown to be unpredictably absorbed and utilized.



      ANDRIOL 40mg (Italy)
      One might also pay interest to the "mildness" of Andriol as described by other bodybuilding materials. Andriol is often spoken about as some type of magic product, which to spite being a form of regular testosterone somehow allows for only minimal estrogen conversion. You should know that the way a drug is administered includes a number of factors that can slightly alter its effect, the most predominant being the speed of release. This effects the time it takes for a peak blood level to be reached, and likely the length it takes to see results. The primary reason testosterone suspension seems more powerful than enanthate is because more drug is active on day one. At the same time estrogen builds up faster and side effects become pronounced very quickly. The ester is also part of the total weight, and 100 mg testosterone contains a much larger quantity of testosterone molecules that testosterone plus ester, another reason for varying effect. But these changes do not amount to all that much. The structure of testosterone is what allows it to break down into estrogen. The only way we can really prevent an androgen from converting to estrogen is to change the base molecule, not the ester. Once free in the blood stream we cannot prevent testosterone from being aromatized without interfering with the aromatase enzyme itself. The lack of results and side effects often reported with Andriol must be going hand in hand with poor absorption.


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