Nolvadex has been seen to cause ocular damage after prolonged use(5+ yrs)
Now, you don't want to take Nolva every 4-5 days becasue the 1. it would take you a couple of months to reach steady state plasma levels. 2. Half life is 5-7 so EOD would be needed to at least keep a consistant level.
Rule of thumb, it takes about 5x the half life to reach steady state blood levels. So taking it every 4-5 days would put your time frame at about 90 days.
Nolva also lowers IGF by considerable amounts. I'll pull a study on that from pubmed if you like.
I personally run .5mg of L-dex + 10mg of Nolva along side for it's SERM benefits. I figure the lipid benefit outweighs the IGF negative(and at 10mgED, IGF won't be hindered that much)
"The tragedy of life is not found in failure but complacency. Not in you doing too much, but doing too little. Not in you living above your means, but below your capacity. Never failure but low aim, is life's greatest tragedy"- Benjamin Mayes
"The power of accurate observation is commonly called cynicism by those who have not got it"- George Bernard Shaw