TweetThe few times that I used winny I felt the effects within 1 week. You can look for your hair to start falling out like a shedding dog, joint stiffness for some of the negative side effects. Muscle hardness and strength will go up as well as muscle striations will appear if your bf is low enough. I personally do not respond well to winny and all i ever got was a little strength and some really sore joints in my hands and knees.