GH?? arguement (take in morning or night)

[Bigdan322]

TweetOk, heres the deal I got into an arguement with a friend who is a juice monkey just like the rest of us. He said you are supposed to take your growth in the morning and i said (though i have never taken it) that i read somewhere that its to be taken twice a day, mid afternoon and night. would someone care to settle this arguement for us.

[FUZO]

TweetIMO ONCE A DAY AND WHO CARES WHEN.HOW ABOUT THE SAME TIME EVERY DAY EITHER AM OR PM I NEVER HEARD OF SPLITTING GH UP DURING THE DAY BUT I COULD BE WRONG, SOME ONE ELSE WOULD LIKE TO ELABORATE

[Bigdan322]

Tweetwho cares? do you know how expensive growth hormone is? If i were him i'd want to know that i was using the stuff correctly so that i was getting the most out of something that expensive. everyone that knows about this stuff has an opinion on when the best time is to take it, I'd say at night a few hours before bed because you do most of your growth and muscle repair at night. Admittedly he should have found out about this before he spent the money.

[blink]

TweetActually, you want to avoid bedtime injections since we produce the bulk of our own GH in the first two hours of sleep. Since exogenous GH suppresses this, you should not take it before bed.

The half-life of GH is only 2 hours so spread it out, use mid-morning and late afternoon after lifting.... both flat times in our natural GH production.

[DIRTY_SOUTH]

Tweetexactly

[FUZO]

TweetCOME DECEMBER WILL BE MY FIRST TIME USING IT.

[SMILEY FACE]

Tweettwice a day 1 in the mornig and the other after lifting

[BM]

Tweet^^^
ditto

[DangerousGround]

TweetIf I ever can afford some I will look the info up.

[Bigdan322]

TweetYeah that does make sense, that way you get a hit in the morning noon and your body's own natural GH at night. Blink you said synthetic GH suppress your natural GH so does that mean that after you discontinue use of GH you will have a lull in natural levels just like post cycle crash from a test cycle? Thanks for the help guys.

[Muraco]

TweetMost of the top competitors here at Gold's northern California take it at night right before bed. I'm using 3IU's per day, 1.5 mid-afternoon and 1.5 before bed. GAined 12 pounds on it during this first month and a half, although I know most is water.

[Raoul3]

Tweet

Originally posted by blink
Actually, you want to avoid bedtime injections since we produce the bulk of our own GH in the first two hours of sleep. Since exogenous GH suppresses this, you should not take it before bed.

The half-life of GH is only 2 hours so spread it out, use mid-morning and late afternoon after lifting.... both flat times in our natural GH production.

Actually some figures suggest suppression doesn't even start 4 hours after injection... So the optimal time should be right before bedtime and not earlier in the evening. You should still benefit from your own production this way.

Read this post by Nandi12 on cuttingedgemuscle.

"The human response to exogenous GH is really variable, as can be seen in figures 1 and 2 in this study.

https://jcem.endojournals.org/cgi/co...ll/85/2/601#R31

To quote from the paper:

Although the mean serum 22K-GH levels after injection were not different even at higher doses compared to the placebo group during the first 4 h, the 22K-hGH levels were reduced even at lower doses from approximately 4–6 h up to 12 h. During the subsequent 24-h observation period, the 22K-hGH levels gradually returned to the placebo level.

So suppression does not even begin until 4 hours after injection, and can last for many hours after that, as the abovementioned figures show. The reason there is a lag of a few hours is because it takes several hours for IGF-1 (which suppresses GH) to rise after a GH injection. See fig 4.

The lower figures of 4 to 6 hours of suppression after an injection are from rat studies:

In previous studies (31, 32), single intramuscularly or sc administration of hGH (with monitoring of the resulting plasma profiles) showed a delayed and prolonged suppressive effect on rat GH secretion. The time course of endogenous GH suppression in rats was similar to but faster than that in humans reported here. The fast time course in rats was probably due to the rapid absorption of hGH in this species (14, 33)."

[justgettinbig]

Tweetbeen on gh for 4 months now on my third kit take 2iu in morning and 2iu evening before work out