TweetLet’s examine M-Tests All-Star cast of ingredients:
Fadogia Agrestis PE:
Fadogia Agrestis is an herb that is indigenous to Africa that has been used for centuries as a male aphrodisiac and has been shown in rodent studies to potently increase testosterone and boost libido .
Unlike other aphrodisiacs, Fadogia Agrestis has also demonstrated an ability to increase ejaculation latency; potentially allowing men to last longer in bed .
Several studies have implicated the Saponin content of Fadogia in enhancing testosterone and aphrodisiac properties through the increase of luteinizing hormone (LH) within the body. Under normal conditions LH is released in order to maintain testosterone within a given range, however as LH is increased, this allows the stimulation of increased testosterone production [1, 2].
Urtica Dioica (Stinging Nettle) is an herb that may help increase free testosterone levels while also helping to reduce dihydrotestosterone (DHT) .
Urtica Dioica & Free Testosterone:
Urtica Dioica contains lignans that have the ability to bind to sex hormone binding globulin (SHBG) and inhibit its binding to its specific receptor [3, 4]. This allows for more free testosterone to circulate in the blood. This is important because it is free testosterone that is responsible for most of the beneficial effects that people associate with testosterone. Bound testosterone is not available to the cell receptor sites and does not participate in the muscular development and libido effects [5, 6].
An interesting note: As males age, falling testosterone levels can lead to decreased libido, weight gain, muscle loss, and other negative effects. As testosterone levels drop, SBHG levels begin to rise and may increase by as much as 40% .
Urtica Dioica & DHT:
Urtica Dioica has been shown by researchers to be beneficial for prostate health . Dihydrotestosterone (DHT), a metabolite of testosterone, can stimulate prostate growth which can lead to a variety of negative issues including prostate problems and hair loss . Urtica Dioica contains components that may inhibit the binding of DHT to various sites around the prostate membrane thereby helping prevent benign prostatic hyperplasia . Also, Urtica Dioica may help inhibit an enzyme known as 5-alpha reductase. This enzyme is responsible for conversion of testosterone into dihydrotestosterone (DHT) [5, 8].
KSM-66® Ashwagandha Root Extract:
KSM-66® is a high quality Ashwagandha extract produced by Ixoreal that was in development for over 14 years. Ashwagandha is an adaptogen herb that is commonly associated with helping with anxiety . In the case of KSM-66®, it has also been shown to improve semen quality by increasing serum levels of testosterone and luteinizing hormone (LH), while reducing levels of Follicle Stimulating Hormone (FSH) [10, 11].
In addition to helping optimize important anabolic hormones, Ashwagandha helps reduce levels of cortisol in the body. Cortisol is a catabolic hormone in the body and chronically elevated levels of it can suppress testosterone production and inhibit anabolism [12, 13].
Eurycoma Longifolia (Tongkat Ali):
Eurycoma Longifolia is also known as Tongkat Ali and Long Jack. It is a Southeast Asian botanical that has traditionally been used to promote natural testosterone production and help promote libido, enhanced energy levels, endurance, stamina, and more [14, 15, 16].
Tongkat Ali exerts much of its aphrodisiac properties through its glycoprotein and eurypeptide content, and its testosterone enhancement capability through its ability to increase luteinizing hormone and increase the rate in which free testosterone is unbound from its binding hormone, sex hormone binding globulin (SHBG) [14, 15].
In addition to this, several human trials have demonstrated Tongkat Ali’s ability to increase lean mass in both young and middle aged males whilst also improving their stress hormone profile (decreasing cortisol, and other subjective markers of stress) which helps augment an overall anabolic environment and improve quality of life [14, 15, 16].
PrimaVie® Shilajit Extract:
PrimaVie® is a clinically proven and highly quality Purified Shilajit from the Himalayas that has been shown in studies to significantly increase free and total testosterone levels, as well as improve physical performance and reduce fatigue [17, 18]. In one human trial, Shilajit was able to markedly enhance the extracellular matrix gene expression responsible for skeletal muscle adaptation, making it one of the only ingredients to augment the effect of exercise in this manner .
In another study involving 60 infertile men, Shilajit supplementation was able to improve sperm count by over 60%, improve sperm motility by nearly 40%, and increase levels of testosterone by 23.5% through a reduction in circulating free radicals . To further back this up, another study involving 75 males demonstrated a 20% increase in total testosterone and a 19% increase in free testosterone .
Boron is a trace mineral that has scientific evidence supporting its use for increasing testosterone and free testosterone levels. It also has scientific evidence supporting its ability to decrease estrogen levels .
A scientific study on eight healthy male volunteers showed that subjects supplementing with 10 mg. of boron significantly increase free (active) testosterone levels and decreased estrogenic activity as measured by a significant decrease in estradiol after only seven days. These results showed a 28% increase in free testosterone and a 39% decrease in free estrogen levels 
Another study that was conducted to look at how boron supplementation impacts serum vitamin D levels also measured free testosterone levels. After 2 months of giving 13 male subjects 6 mg. of boron daily, researchers observed that free testosterone levels had increased by an average of 29.5%. This number is consistent with the results of the study mentioned above [20, 21].
In addition to its testosterone boosting benefits, boron has also been researched &/or commonly used for inflammation, bone maintenance, cognition and learning benefits, and osteoporosis [19, 20, 21].
Mucuna Pruriens is an adaptogenic herb that may help increase LH (Luteinizing Hormone) which can lead to increases in testosterone production and release. It may also help elevate levels of growth hormone (GH) in the body and lower prolactin levels by increasing dopamine neurotransmitter synthesis.