Re: PEGylated MGF Profile
PEGylated MGF dosing Protocols
The PEGylated version is going to be much longer lasting making a 1-2 dose per week procedure possible. I still think its best used with IGF or AAS to maximize the benefits so here are some sample protocols
Once a week PEG MGF/ IGF
Sunday 100-300 mcg MGF you can choose to site inject if you wish. I think splitting large doses may benefit.
Monday –Fri IGF 50mcg e/d
Twice a week PEG MGF / IGF
Sunday and Wed MGF 50-150 mcg
MT, ThF IGF 50 mcg
These protocols are just to start as this is brand new feel free to tweak them if you like. I will update them after we have done some testing.
Re: PEGylated MGF Profile
Re: PEGylated MGF Profile
Wow no one is interested in what may be the biggest peptide to reach the market since IGF?
Re: PEGylated MGF Profile
interested.....but need more testing and dosing info. I'm running igf right now with some good results. nothing huge but its qaulity muscle.
Re: PEGylated MGF Profile
below is your words on another thread about mgf profile.there you state that original mgf is stable in someone's system for 12-24 hours.now im sure this was back when IBE was trying to sell plain mgf right? ok,so now IBE comes out with pegylated mgf(which has been around since before anyone got their hands on any mgf,so why didnt they do their research sooner,anyway).so,now your statement is that plain mgf or synthetic is only stable for a matter of minutes due entering the blood stream or something to that effect right? ok,so which are you sure is correct now? your trying to push a new product for IBE and telling everyone that "oh,wait all that plain mgf that IBE sold you is useless,you need to get this new pegylated mgf from IBE.this will work"............im a little confused so say the least.........
Methods of use:
MGF inhibits differentiation, which is the actual fusing of the myoblast to the myotubule. So to optimize the effects of this one would want to try and take the MGF in a manner that differentiation would not be effected post work out.
With the original version of MGF, it is only stable in your system for 12-24 hours. So taking it the day before a workout would provide sufficient time for the MGF to wear off.
If one wanted to maximize the effects of MGF they could stack it with something that increased differentiation. In the case of IGF, the would want to take this on days they don't take MGF, or in the case of AAS it would depend on the types of AAS and the esters.
Some sample MGF/IGF protocols
3 day HST method
MGF sun, tue, thur
IGF mon tue wed (workout days)
4 day split
Sun MGF upper body
Monday MGF lower body IGF upper body
Tue IGF lower body
Repeat thur/fri
5 day split
B/C MGF is not stable in the bloodstream, it will not effect the muscle you don't inject. So as long as you are using the original MGF you could inj MGF and IGF on the same days without worrying about conflicts b/t the peptides.
Just inj the MGF in the muscle you will owrk the following day.
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Researcher, Biochemist, FBaller, IBE MOD
Re: PEGylated MGF Profile
when the MGF first came out we had limited research to go off of and we still do. But the original studies suggested a 12-24 life time in serum in vitro. Later studies have shown than in Vivo life time of the peptides is even shorter, much shorter.
This is a cost of being innovative and trying to be the first to bring things to the market. The PEG has shown good results for increased life time in vivo in neurological studies. So I am confident that it will work awesome b/c I saw results from the MGF reguardless the short time. They just werent ass good as I hoped. I'm starting the PEG next week. So I will be able to comment from first hand expereince of the difference.
Re: PEGylated MGF Profile
Quote:
Originally Posted by The Game
when the MGF first came out we had limited research to go off of and we still do. But the original studies suggested a 12-24 life time in serum in vitro. Later studies have shown than in Vivo life time of the peptides is even shorter, much shorter.
This is a cost of being innovative and trying to be the first to bring things to the market. The PEG has shown good results for increased life time in vivo in neurological studies. So I am confident that it will work awesome b/c I saw results from the MGF reguardless the short time. They just werent ass good as I hoped. I'm starting the PEG next week. So I will be able to comment from first hand expereince of the difference.
OK,at least your being honest.i would like you to know that IBE who you are( i think affiliated with,if im wrong then i appologize),is trying to say that plain mgf doesnt work at all.by your own admission you state that you saw results regardless its limited half-life.thank you.
later
Re: PEGylated MGF Profile
I saw results, but that just means that the peptide works, but not significantly enough to produce significant muscle gains. Its a waste b/c of the short life
Re: PEGylated MGF Profile
Here it is plain and simple for you. Without any complex peptide understanding required other than the fact that PEGylation increases the stability, and lifetime of the peptide.
MGF is responsible for increasing muscle stem cell count through a process called proliferation.
https://www.science.org.au/future/images/rr.gif
As you see the effect going left to right here is exponential. The more stem cells you have the more that can be stimulated and replicated. In order to singal this replication there has to be sufficient saturation of cell receptors. Because attachment to a receptor is by simple probability, the more peptide and the more time the more probable a cell will reach saturation and begin to replicate.
IF regular MGF has a shorter life span, it has a significantly smaller chance at saturating cells. It is not stable in the blood so its only real chance to bind is right at injection. If you calculate probability of binding via (time x concentration) and then PEG last appx 300 times longer, the probability of MGF having a significant effect is about 300 times at the same dosage. In other words you would need 300 times the regular MGF to bind to as many receptors as the PEGylated version. And even at that case the loss of peptide to the blood so fast would still limit the effects of MGF.
Now you must also consider the cumulative effects of having longer term MGF action. AS you saw in the image, the number of receptors will increase, this increase the probability further for the PEG version so now every time you undergo muscle stem cell replication within the 4-8 days the PEG version is active you increase the probability proportional to the increase in cell number.
So without knowing anything more than multiplication and the law of probability one can see that PEG MGF is significantly more effective.
Re: PEGylated MGF Profile
Quote:
Originally Posted by The Game
I saw results, but that just means that the peptide works, but not significantly enough to produce significant muscle gains. Its a waste b/c of the short life
your statement didnt sound like this before.just doesnt sound right now that your gang has a new product out and"oh my" all of a sudden it was a waste to take that plain mgf.i dont think so.like i said about IBE people know what you guys are about.we are not stupid.
Re: PEGylated MGF Profile
You can take all the MGF you want I don't care. I'm here to educate. You choose not to learn, you choose not to grow. Thats your perogative. I have answered all your questions on every other board you tried to start trouble on.
Re: PEGylated MGF Profile
so does it work or not?? the bottom line is that if its worth me buying......i'll leave the science and research to the nerds. just load the syringe already.
Re: PEGylated MGF Profile
The PEGylated version is hundreds times more effective overall. Thats the one I would consider worth buying.
Re: PEGylated MGF Profile
I'm thinking on an end of summer bash with that stuff. I'll let you know how it goes i guess....
good info by the way. nice to have guys willing to share....