when the doc put me on it for insulin resistance he went with 500 1x per day and it helped my fasted glucose quite a bit. we had no need to go above the one 500mg daily dose. something else that we have tinkered with and i still do is using either lantus treseba or humalog. with the first 2 it is one 5-10iu injection daily and if you go the log route then you do 3-6iu with your heavier carb meals. the theory and thought process is that it allows the pancreas beta cells to recover and bring insulin sensitivity back. i did learn of it from palumbo but also had the conversation with my doc and see if he thought it would work. i did it pretty effectively this past year with no issues at all. i will say and i know you cant use it but i keep berberrine in at 500 at a min daily and i increase it to 1500 or 2g when i have cheat meals.
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