Didn't respond favorably to Sermorelin . initial bw showed my IGF-1 at 108, I was then prescribed by DEFY 1000 mcgs nightly. After 4 months of nightly injections and no carbs 3hours before bed my IGF-1 went to 138. Needless to say I was disappointed. I'm not sure what happened, but im not a fan of the APS that was used. I stopped buying it after the consult with DR Saya. I'm now using Sermorelin with Ghrp2 200mcg nightly and my sleep quality, skin and sex drive have improved nicely. I will be checking my labs in the future and hopefully my IGF-1 levels will improve. The new products of Sermorelin with ghrp2 are provided by a local MD and not DEFY.