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Acetyl-L-Carnitine & Pantethine Prevent Damage to the Blood Brain Barrier

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  • Acetyl-L-Carnitine & Pantethine Prevent Damage to the Blood Brain Barrier

    Your blood brain barrier (BBB) must keep unwanted substances out of your brain. If it becomes “leaky” due to inflammatory, stress, pollution, etc. then problematic substances can cross into your brain and a chain reaction of damaging events follows. Such problems with blood brain barrier integrity are a percentage of the problem in just about every issue affecting the health of your brain, including reduced learning ability, memory decline, cognitive decline, depression, and any neurologic disease. Nutrients such as Acetyl-L-Carnitine (ALC) and pantethine can help preserve the integrity of your BBB, thus reducing nervous system stress.
    One of the most common compounds in widespread use that damages your BBB is excess alcohol intake. Excess alcohol is known to set off an inflammatory free radical reaction at the BBB, making it permeable not only to alcohol damage but from any other toxins also in the bloodstream at the time of alcohol intake (which is typically a wide range of toxins from digestive origin).
    A new study has shown that ALC can prevent damage from alcohol to the BBB. It was found that ALC boosted up the antioxidant enzymes that naturally protect the BBB, giving the BBB extra support to deal with a toxic challenge.
    These researchers also note that the metabolic breakdown product of alcohol, acetaldehyde, also induced injury to the BBB. Acetaldehyde is also a byproduct of Candida albicans, which is why people with an overgrowth of Candida have brain fog and other neurologic problems. It is known that pantethine fuels the production of the key enzyme, aldehyde dehydrogenase, that clears acetaldehyde. Furthermore, pantethine has been shown to prevent inflammation at the BBB. This affect was so powerful that it was able to prevent malaria from entering the brain.
    ALC and pantethine are known to help brain function in multiple ways. One way is to protect your BBB so that substances that should be kept out of your brain stay out of your brain.


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