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Researchers at the University of Granada in Spain studied elite runners participating in a 50-kilometer run.
by Robert Goldman MD
Co-enzyme Q10—also known as ubiquinone—is a powerful antioxidant found in every cell of the body, where it has important functions within the mitochondria, the “powerhouses” of cells. Researchers at the University of Granada in Spain studied elite runners participating in a 50-kilometer run that combined several types of high effort, including mountain runs and ultra-endurance work. Twenty athletes were divided into two groups: one group received one 30-milligram capsule of Q10 two days before the run, three 30-milligram capsules the day before the run and one capsule one hour prior to the run. The other group received a placebo at the same time.
Whereas the placebo group displayed a 100 percent increase in oxidative stress markers, only 37.5 percent of the Q10-supplemented runners experienced the same stresses. Suggesting that Q10 countered the overexpression of certain pro-inflammatory compounds after exercise, the researchers conclude that “co-Q10 supplementation before strenuous exercise decreases the oxidative stress and modulates the inflammatory signaling, reducing the subsequent muscle damage.”
Diaz-Castro, J., et al. (2011). Coenzyme Q10 supplementation ameliorates inflammatory signaling and oxidative stress associated with strenuous exercise. European J Nutrition. Published online October 12.
by Robert Goldman MD
Co-enzyme Q10—also known as ubiquinone—is a powerful antioxidant found in every cell of the body, where it has important functions within the mitochondria, the “powerhouses” of cells. Researchers at the University of Granada in Spain studied elite runners participating in a 50-kilometer run that combined several types of high effort, including mountain runs and ultra-endurance work. Twenty athletes were divided into two groups: one group received one 30-milligram capsule of Q10 two days before the run, three 30-milligram capsules the day before the run and one capsule one hour prior to the run. The other group received a placebo at the same time.
Whereas the placebo group displayed a 100 percent increase in oxidative stress markers, only 37.5 percent of the Q10-supplemented runners experienced the same stresses. Suggesting that Q10 countered the overexpression of certain pro-inflammatory compounds after exercise, the researchers conclude that “co-Q10 supplementation before strenuous exercise decreases the oxidative stress and modulates the inflammatory signaling, reducing the subsequent muscle damage.”
Diaz-Castro, J., et al. (2011). Coenzyme Q10 supplementation ameliorates inflammatory signaling and oxidative stress associated with strenuous exercise. European J Nutrition. Published online October 12.