Tweetinteresting.. so i guess we better load up on em pain killers... lol

TweetDUDE.. AND I TRY AND NOT TAKE ADVIL CAUSE ITS BAD FOR YOUR LIVER.. THATS A COOL ARTICLE....THANKS

Tweetwow, who'd have thought? good article

Tweet

Originally Posted by daved150

I thaught this was interesting.....



Pain Killers Increase Muscle Mass

Over-The-Counter Pain Killers Increase Muscle Mass

Written by Federation of American Societies for Experimental Biology


ScienceDaily (Apr. 7, 2008) - Taking daily recommended dosages of ibuprofen and acetaminophen caused a substantially greater increase over placebo in the amount of quadriceps muscle mass and muscle strength gained during three months of regular weight lifting, in a study by physiologists at the Human Performance Laboratory, Ball State University.

Thirty-six men and women, between 60 and 78 years of age (average age 65), were randomly assigned to daily dosages of either ibuprofen (such as that in Advil), acetaminophen (such as that in Tylenol), or a placebo. The dosages were identical to those recommended by the manufacturers and were selected to most closely mimic what chronic users of these medicines were likely to be taking. Neither the volunteers nor the scientists knew who was receiving which treatment until the end of the study.

All subjects participated in three months of weight training, 15-20 minute sessions conducted in the Human Performance Laboratory three times per week. The researchers knew from their own and other studies that training at this intensity and for this time period would significantly increase muscle mass and strength. They expected the placebo group to show such increases, as its members did, but they were surprised to find that the groups using either ibuprofen or acetaminophen did even better.

An earlier study from the laboratory, measuring muscle metabolism (or more precisely, muscle protein synthesis, the mechanism through which new protein is added to muscle), had looked at changes over a 24 hour period. This "acute" study found that both ibuprofen and acetaminophen had a negative impact, by blocking a specific enzyme cyclooxygenase, commonly referred to as COX.

But that study looked at only one day. Over three months, says Dr. Trappe, the chronic consumption of ibuprofen or acetaminophen during resistance training appears to have induced intramuscular changes that enhance the metabolic response to resistance exercise, allowing the body to add substantially more new protein to muscle.

The amount of change was measured in quadricep muscles using Magnetic Resonance Imaging (MRI), the gold standard for determining muscle mass. The researchers now are conducting assays of muscle biopsies taken before and after the three-month period of resistance training, in order to understand the metabolic mechanism of the positive effects of ibuprofen and acetaminophen.

One of the foci of Ball State's Human Performance Laboratory is the adaptation of the elderly to exercise. Another is the loss of muscle mass that takes place when astronauts are exposed to long-term weightlessness. This work has implications for both groups, says Dr. Trappe.

*This presentation was part of the scientific program of the American Physiological Society (APS). In addition to Dr. Carroll and Dr. Trappe, co-authors of the Experimental Biology presentation are Jared Dickinson, Jennifer Lemoine, Jacob Haus, and Eileen Weinheimer, graduate students working with Dr. Trappe, and study physician Dr. Christopher Hollon.

Funding for the research came from the National Institutes of Health and a postdoctoral initiative award from APS.

Adapted from materials provided by Federation of American Societies for Experimental Biology, via EurekAlert!, a service of AAAS.

I remember reading a "study" that suggested pain killers limit muscle mass a while back.

Thanks for the post dave

Tweetthat is either brand new cutting edge research or it's flawed. i read in almost every muscle magazine almost monthly that high levels of ibuprofen and nsaids will stop your training progress in its tracks. there was a write up about dudes who train on real heavy duty pain meds and the aspirin or tylenol3 with codein or 5/325 vicodins will slow down your gains and ironically you'd be better off with a scedule 2 controlled substance like straight hydrocodone or oxycodone with no aspirin while training, despite the effect it would have on your respiration, slowing the rate of oxygen uptake down, at least you wouldn't have the nsaid action screwing with you. yet another reason why training on nubain came into vogue late 90's into the 2k's, it gave you a mild high and blocked pain receptors but didn't affect muscle gains like nsaids did. very surprised to hear about a positive piece on these involving training.

TweetI agree with BD. I have always heard the opposite.

TweetInteresting....

Tweet

Originally Posted by BigDawg

that is either brand new cutting edge research or it's flawed. i read in almost every muscle magazine almost monthly that high levels of ibuprofen and nsaids will stop your training progress in its tracks. there was a write up about dudes who train on real heavy duty pain meds and the aspirin or tylenol3 with codein or 5/325 vicodins will slow down your gains and ironically you'd be better off with a scedule 2 controlled substance like straight hydrocodone or oxycodone with no aspirin while training, despite the effect it would have on your respiration, slowing the rate of oxygen uptake down, at least you wouldn't have the nsaid action screwing with you. yet another reason why training on nubain came into vogue late 90's into the 2k's, it gave you a mild high and blocked pain receptors but didn't affect muscle gains like nsaids did. very surprised to hear about a positive piece on these involving training.

thats why i thaught it intresting...i've always read the same thing, but never seen any report or results of studies done...just the typical "not good for muscle gains" type stuff. this studt is a recent study....i've been avoiding them for years becouse of shyt i read

Tweeti would be willing to bet that the only reason that there muscle mass went up was because they didn't hurt as much as the placebo group and for god sakes these people were old so probably had lots of pains being on a small amount of pain killer probably just made it so they could hit a full range of motion and actually work out without feeling liek they were going to die

TweetWell....this one time.....I took an anti-inflamatory with a viagra and nothing happened.

Tweetare you sure it wasn't a blue flinstone vitamin? the betty vitamin doesn't give as profound a reaction as real viagra, but the wilma??? she gets my rod hard every time.

Tweethmmm... the fact that they only tested on old people should give a clue. I highly doubt you would find any research indicating that this would be beneficial to say the 20-40 age group. The only reason its beneficial is, as James said, cuz they don't have any pain or inflammation (likely from arthritis) that would restrict their range of motion.