Tweet#2


bromo
Ingredients
Each tablet contains: Bromocriptine mesylate 2.87 mg (equal to 2.5 of base bromocriptine)
Excipients Colloidal silica, magnesium stearate, polyvinyl pyrrolidine, corn starch, lactose.

Parlodel Is Available In
Boxes containing 30 2.5-mg tablets, to be taken by mouth.

Pharmaceutical Classification
Prolactin secretion inhibitor with dopaminergic effect.

Parlodel Is Recommended For
Galactorrhoea accompanied or not by amenorrhoea; post-partum effects (Chiari-Frommel); idiopathy (Aragonz-del Castillo); tumoral effects (Forbes Albright), side effects from pharmaceutical products (psychotropic and contraceptive drugs). Prolactin-dependent amenorrhoea without galactorrhoea. Hyperprolactinaemic infertility. Menstrual disorders (premenstrual syndrome, brief luteinic phase) Prolactin-dependent male hypogonadism Acromegaly: The initial treatment for this problem is surgical or by means of radiotherapy. PARLODEL is a useful adjuvant in either treatment and may be used without them in certain cases.

Idiopathic and arteriosclerotic Parkinson's disease. PARLODEL is particularly beneficial to those patients who show a decreasing response to L-dopa, and in cases where the effects of levodopa therapy are restricted by the presence of the "on-off" phenomenon. Taking this product with L-dopa brings about an increased anti-Parkinson effect which permits a lower dosage of both pharmaceutical products. PARLODEL can be taken on its own in preliminary or mild cases of Parkinson's disease and may also be taken with anticholinergic drugs and/or other anti-Parkinson products.

Contraindications
If you are expecting a baby or think that you might be, it is unwise to take this product.

The safety and effectiveness of PARLODEL (bromocriptine mesylate) has not been confirmed for treatment of adolescents younger than fifteen years of age.

Precautions
In patients with galactorrhoea and prolactin-dependent amenorrhoea, menstrual disorders or acromegaly, PARLODEL may eliminate pre-existing sterility. Women who may become fertile but who do not wish to conceive should therefore adopt a mechanical form of contraception. The exact cause of infertility should be determined before beginning PARLODEL treatment.

Pregnancy should be avoided if hypophysial adenoma has been diagnosed. A marked lengthening of the sella turcica or a defect in the field of vision requires, first of all, surgery or radiotherapy. PARLODEL is only recommended should these measures fail. In the absence of hypophysial adenoma and should the patient be anxious to conceive, PARLODEL treatment should be stopped as soon after conception as possible (early pregnancy diagnosis with immunological test) since knowledge of the possible effects of this pharmaceutical product on the development of pregnancy and the fetus is as yet inconclusive. As a precautionary measure in the case of confirmed pregnancy, the possible negative effects of a pathological hypophysial problem associated with the pregnancy should be controlled regularly (for example, checking the field of vision).

Sporadic gastrointestinal bleeding has been known to occur in patients with acromegaly, whether they are undergoing PARLODEL treatment, another treatment, or no treatment at all. Until more complete information is available, it is thus preferable for acromegaly patients with case-histories of peptic ulcer to receive some other form of treatment. If it is essential that such patients take PARLODEL, they can soon expect signs of such gastroenteric reactions.

Caution is advised when PARLODEL is taken in large doses by patients suffering from Parkinson's disease with case histories of psychotic disorders, serious cardiovascular problems, peptic ulcers or gastroenteric bleeding.

Some cases of pleural effusions have been reported in Parkinson patients undergoing long-term high-dosage PARLODEL treatment. Although the causal correlation between PARLODEL and these reports has not been proved, it is still advisable for patients who show inexplicable pleuro-pulmonary signs or symptoms to be examined and the possibility of stopping PARLODEL treatment considered.

Interactions With Other Medicines
The possibility of interactions between bromocriptine and psychoactive or hypotensive drugs should not be ruled out. Particular caution should be taken with regard to patients undergoing treatment with ergot alkaloids or products which might possibly increase arterial pressure.

Special Warning
For instructions as to the use of this product during pregnancy or by patients with acromegaly and/or hypophysial adenoma, see "PRECAUTIONS". Treatment must be carried out under medical supervision, including hormone dosage and gynaecological consultation. All women being treated with PARLODEL for a continuous period of longer than 6 months should have gynaecological check-ups once a year if they have not reached menopause, and every 6 months if they are undergoing menopause (with cervical and if possible endometrial cytology). Women with affections not linked to hyperprolactaemia should take the lowest possible effective dosage of PARLODEL to alleviate the symptoms, so as to avoid the possibility of lowering the prolactin level below normal with a consequent alteration of the luteinic function. Tests concerning plasmatic prolactin and post-ovulatory progesterone should be carried out on such patients if treatment is prolonged for longer than 6 months. In the event of hypotensive reactions, which can occur with certain patients especially during the first days of treatment, particular care should be taken when driving or operating machinery.

Directions For Use
This product is always to be taken at mealtimes. Galactorrhoea and/or prolactin-dependent amenorrhoea, hyperprolactaemic infertility: half a tablet 3 times daily. If this is not sufficient, increase the dosage gradually to 1 tablet, 2-3 times daily with meals. Continue the treatment until the mammary secretion disappears completely, and, should the problem be compounded by amenorrhoea, until the menstrual cycle returns to normal. The treatment may be continued if necessary for several menstrual cycles in order to avoid a relapse. Disorders of the menstrual cycle:- Pre-menstrual syndrome. Begin treatment on the 14th day of the menstrual cycle with a half tablet per day, then gradually increase the dosage by half a tablet until reaching the dosage of 1 tablet twice daily. Continue this treatment until the onset of the menstrual flow.

Brief luteinic phase. Half a tablet 3 times daily, gradually increasing the dosage to 1 tablet twice daily with meals until the luteinic phase has returned to normal.

Male hypogonadism: half a tablet 3 times daily, gradually increasing to 1 tablet 3 times daily for a period of 2-3 months.

Acromegaly: Start by taking 1 tablet per day, gradually increasing the dosage over 1-2 weeks to 4-8 tablets, according to the patient's needs, clinical response and tolerance. The daily dosage should be divided into 4 separate and equal doses.

Parkinson's disease: The effects of Parkinson's disease can be combated with low doses, 10-15 mg daily. The effective therapeutic dosage when PARLODEL is taken alone is usually high (30 mg or more per day).

However, if PARLODEL is taken together with L-dopa, with or without the dopa-decarboxylase inhibitor, a lower dosage may suffice. The recommended initial dosage is 2.5 mg twice a day (at mealtimes) for a week. The dosage increase must be gradual and regular: normally not by more than 5 mg every 2-3 days in the initial phase of treatment. Later on, the final dosage increase can be done gradually, not more than 10 mg at a time, depending on therapeutic response and tolerance. Similarly, each reduction of the L-dopa dosage must be gradual until optimum results are obtained. In certain cases L-dopa treatment may be stopped altogether.

In Case Of Overdose
Cases of life-threatening overdoses have not been reported. The single maximum dose taken by an adult has been 225 mg. Nausea, vomiting, dizziness, orthostatic hypotension, excessive perspiration and hallucinations have been observed. Treatment of acute intoxication is symptomatic. Metoclopramide may be used for vomiting and hallucinations.

Adverse Effects
During the first days of treatment, some patients may experience mild nausea and, less frequently, dizziness, fatigue or vomiting. However these side effects have never been of such an intensity as to require a suppression of treatment.

In rare cases, PARLODEL may lead to a lowering of blood pressure. For this reason supervision and evaluations of out-patients are advisable during the early days of treatment. Should such undesired side effects persist, the dosage should be reduced.

Reversible pallor in fingers and toes caused by cold should be reported in the case of patients undergoing a prolonged treatment of 20 mg and more, especially in patients who have previously suffered from Raynaud's phenomenon.

There have also been cases of vasospasm, hallucinations and confusion, hypotension and diskinesia.

Constipation, drowsiness and, less frequently, psychomotor excitation, leanness of the jaw and leg cramp have also been reported during treatment of Parkinson's disease with PARLODEL.

At times certain dose-dependent effects may be controlled by a lowering of the dosage. Postural hypotension may be unpleasant but can be treated symptomatically.

If, after taking this pharmaceutical product, the patient notes unpleasant side effects which are not described in this leaflet, he should consult his family doctor.

Special Storage Precautions
Store this product out of the sunlight and at a temperature not exceeding 25°C

Tweet#3 (and my Favorite)



By Serge Kreutz
October 2002


Bromocriptine is a well-established drug for two conditions, increased levels of the hormone prolactin and Parkinson's. The best-known brand name is Parlodel. The standard tablet dosage is 2.5 mg.

Bromocriptine also has a sexuality-enhancing effect, though it is not commonly sold for that purpose. Nevertheless, there is little doubt that in many people, bromocriptine will support sexual response. The reason why the drug is not specifically sold as impotence or frigidity medication: a sufficient number of studies to achieve FDA approval for the purpose of sexual enhancement have not been conducted.

In view of the enormous marketing success of Pfizer's Viagra, many pharmaceutical companies are interested in distributing substances that enhance sexual response. However, for "old" drugs, the patents of which have expired, there is little incentive to invest into the necessary clinical trials.

The sexually enhancing effect of bromocriptine is very different from the effect of Viagra (generic name: sildenafil citrate). Viagra works primarily on the sexual organ, providing chemically for better rigidity, or some rigidity in the first place.

Bromocriptine, on the other hand, works on the brain, making a person more receptive for sexual stimulation and creating a frame of mind for more powerful orgasms. Both effects are a logical consequence of the way, bromocriptine is traditionally used… to lower levels of the hormone prolactin, and to increase levels of the neurotransmitter dopamine.

High levels of prolactin are generally associated with a decreased sex drive. So, by lowering levels of prolactin, especially when they are high, bromocriptine increases the interest in sex.

A similar effect is achieved by bromocriptine through the neurological route. Bromocriptine is used as a medication in Parkinson's because it will cause higher levels of the neurotransmitter dopamine. Parkinson's is a disease caused by dopamine levels that are too low. Low dopamine levels normally also cause a loss of interest in sex, and an increased sex drive is a common "side effect" of many Parkinson's medications. One person's side effect is another person's cure.

While the increase in sex drive caused by bromocriptine may be hard to measure, the effect on orgasms is more obvious. Orgasms become more powerful, ironically because they are better controlled. The pre-orgasm plateau phase can last for minutes on bromocriptine, and orgasm will be accompanied by a pronounced histamine reaction (stuffed nose).

Bromocriptine is a prescription drug most everywhere, though in many countries of the world, prescription drugs can be bought over the counter. In countries where prescription drugs are indeed only sold on prescriptions, it is within a physician's discretion to prescribe a drug for conditions for which it has not originally been approved. To get a prescription for bromocriptine, please proceed to https://online-consultation-prescriptions.com. The site offers a straightforward deal. You subscribe and are referred to a doc who issues prescriptions for sexual enhancement (doc’s fee not included in the subscription price). If, for any reason, you should be denied a prescription, the subscription price will be refunded, and the doc won’t charge either. Prescriptions are issued for men between 25 and 65 years of age.

For a substance to be approved as a medication, an illness has first to be defined for which it is a cure. Nowadays, there are many newly defined illnesses, such as clinical depression, attention deficit disorder, erectile dysfunction … conditions, which have previously not been considered illnesses but just part of the individuality of a particular human being.

Some members of our species are smarter than others, and some are happier, and some of the males are more virile than their neighbors. Not to be as smart as a genius, and not to be as virile as one's neighbor aren't diseases in the classical sense. But new illnesses are constantly defined, because the pharmaceutical industry has on hand a medication to overcome the condition. So, if there will soon be a medical condition named Weak Orgasm Syndrome, or Clinical Sex Drive Loss, bromocriptine is a sure medication candidate.

Bromocriptine belongs to a group of drugs derived from the ergot fungus. A more concentrated dopaminergic drug that is also derived from ergot is Dostinex. Dostinex is a new, patented drug, which is why clinical trials have been financed to look into its application to improve sexual function, especially the enhancement of orgasms.

TweetOn a personal note- You would seriously be amazed at how well bromo combats the clomid "blues". I dont know about anyone else, but I get a little emotional on clomid and bromo negates almost ALL of that. the last article is most descriptive of this as related to bromo's physiological functions as applied to sexual functions.

Tweethttps://www.fitnessgeared.com/showthr...&threadid=3112

you should really learn about the cytochrome P450 pathway before jumping on bromo. It has A LOT of drug contraindictions.

Lewd

TweetRead that earlier....I think Im in the clear.

Tweetgood post

Tweetbump

TweetThanks, YJ

Grappler

Tweetthanks brp good info

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Originally posted by YellowJacket
On a personal note- You would seriously be amazed at how well bromo combats the clomid "blues". I dont know about anyone else, but I get a little emotional on clomid and bromo negates almost ALL of that. the last article is most descriptive of this as related to bromo's physiological functions as applied to sexual functions.

Nice YJ!

Tweetvery good read thanks!!

Tweet

Originally posted by YellowJacket
On a personal note- You would seriously be amazed at how well bromo combats the clomid "blues". I dont know about anyone else, but I get a little emotional on clomid and bromo negates almost ALL of that. the last article is most descriptive of this as related to bromo's physiological functions as applied to sexual functions.

You can take bromo with Clomid and it won't combat the other?

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Originally posted by latinsteel
You can take bromo with Clomid and it won't combat the other?

I dont think there is a drug interaction. The twins returned to normal quickly as they always do on clomid and I didnt cry while watching movies on Lifetime, so if there is a drug interaction, I dont know about it and it didnt effect me.