TweetBefore that thread on Nelson was deleted you suggested that I bring up a topic where you can hand me my lunch so to speak. Ok, the topic is Proviron and whether or not it's effective as an anti-e'. Now, there is little in the way of scientific research that proves it acts as an anti-aromatase or anything. My contention here, mainly from personal experience substantiated in part by Big Cat's profile on Proviron is that Proviron prevents estrogen formation, which is what leads to gyno. Proviron is a DHT and acts as an anti-aromatase. Here's what Big Cat has to say...
Proviron has four distinct uses in the world of bodybuilding. The first being the result of its structure. It is 5-alpha reduced and not capable of forming estrogen, yet it nonetheless has a much higher affinity for the aromatase enzyme (which converts testosterone to estrogen) than testosterone does. That means in administering it with testosterone or another aromatizable compound, it prevents estrogen build-up because it binds to the aromatase enzyme very strongly, thereby preventing these steroids from interacting with it and forming estrogen. So Mesterolone use has the extreme benefit of reducing estrogenic side-effects and water retention noted with other steroids, and as such still help to provide mostly lean gains. Its also been suggested that it may actually downgrade the actual estrogen receptor making it doubly effective at reducing circulating estrogen levels.
When challenged he recently posted the following:
Big Cat recently posted the following in regards to his statements on Proviron:
"there is no proven effect of proviron on estrogen management. There is no evidence it acts as an anti-aromatase or anything. Ok, I won't deny it is of course, time has proven its efficacy. But its certainly a poor choice if estrogen blockage is your primary course of action. Proviron would be a good choice to slightly lower estrogen to within maintainable ranges, but for actually inhibiting aromatization I would think something like arimidex is more suited. "
So, my contention is still that Proviron is a DHT and acts as anti-aromatase so if you're erstrogen sensitive and gyno prone Proviron at 25-50mg's ed will reduce estrogen levels, which leads to gyno, while enhancing the potency of testosterone in the body. In order words you kill two birds with one stone - the ultimate anti-e. I have no scientific data to back this up. My challenge to you to find the evidence that invalidates my contention....play ball.....batter up...