all about keeping blood levels stable with both compounds and controlling your prolactin if you have issues. i personally do not have any prolactin issues so i have done so successful with npp and tren. some people though it will absolutely crush. it would be best to go short ester and play around with low test and high test to see what works best for you. i have found that for me, lower end test dosing works best but like i said i dont have any issues with either estro or prolactin