TweetI always stay really lean but if I have a vacation coming up or something I'll take 25 MCG a day of t 3 for like 3 weeks. It all depends on your metabolism some people can get away with 12.5 mcgs I can do that actually. I've never gone as high as 50 but I've known guys that have gone as high as a hundred so it all depends on your body but it will take fat off you.