Thanks guys. I'm running 4iu daily of GH, test, mast, eq and using the t3 to lean out. I am a little worried about supressing my thyroid short and long term. I'm going to stick to the 25 for a couple weeks and check the results. I realize that every step up also ups the risk of losing muscle and messing up my thyroid so I'm leaning toward the lowest dose possible. Great advice from all!