TweetNever used primo. I always thought it was for precontest, until lately. I have herd good things about it here. BUMP

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Tweetvar tren mast. just remember it takes forever to take effect and you need at least 16wks for it to be worth the run. think of it like deca, it takes forever to build up and get working but once it does you will know

TweetI have read not to run other dht steroids with it because they fight for the same receptors .would not want to waste that primo.I'm running it in 6 months with npp,injectable anadrol,and tren ace.

TweetA receptor is like a switch, it is either on or off. No matter what the drug once the drug attaches to a receptor it is on. There are not separate receptors for different drugs, an androgen receptor is an androgen receptor.

Tweet"“For example, some drugs are considered milder (less androgenic), and produce fewer side effects in women and children. Others are more androgenic, which makes them better at supporting sexual functioning in men. Some are injectable medications, and others made for oral administration. There are limits to this diversity, however. All AAS drugs activate the same cellular receptor, and as such share similar protein anabolizing properties.”

Excerpt From: Llewellyn, William. “Anabolics.” iBooks.
This material may be protected by copyright.

Check out this book on the iBooks Store: https://itun.es/us/srDbD.l

TweetAnother excerpt which applies here, although the original question pertains to rotating drugs during a cycle. “No, this is not necessary. Anabolic/androgenic steroids all work primarily by attaching to and activating the same receptor. As such, you do not gain anything by switching to a new compound that works via stimulating the same receptor. If tolerance were induced by one AAS compound, it would be extended to all compounds. The plateau effect that is noticed 6-8 weeks into most cycles is poorly understood, but likely related to the new metabolic limits placed on muscle cells under the influence of a certain AAS dosages, not insensitivity to AAS. Classic downregulation does not occur with these drugs, and even if it did, rotating steroids would not prevent it.”

Excerpt From: Llewellyn, William. “Anabolics.” iBooks.
This material may be protected by copyright.

Check out this book on the iBooks Store: https://itunes.apple.com/us/book/ana...86921298?mt=11

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Originally Posted by chemicallyengineered

Another excerpt which applies here, although the original question pertains to rotating drugs during a cycle. “No, this is not necessary. Anabolic/androgenic steroids all work primarily by attaching to and activating the same receptor. As such, you do not gain anything by switching to a new compound that works via stimulating the same receptor. If tolerance were induced by one AAS compound, it would be extended to all compounds. The plateau effect that is noticed 6-8 weeks into most cycles is poorly understood, but likely related to the new metabolic limits placed on muscle cells under the influence of a certain AAS dosages, not insensitivity to AAS. Classic downregulation does not occur with these drugs, and even if it did, rotating steroids would not prevent it.”

Excerpt From: Llewellyn, William. “Anabolics.” iBooks.
This material may be protected by copyright.

Check out this book on the iBooks Store: https://itunes.apple.com/us/book/ana...86921298?mt=11

^^I'm pickin up what you're puttin down brotha. Absolutely agree with this. I try to explain it to some people with the analogy of a drive in burger joint like sonic or something LOL. When the car is in the parking spot the receptor is full and once it leaves then the receptor is available for the next car LOL.

TweetThere is so many different reads and facts the one that made sense to me was to run a test,19nor and a dht.
Never test and two dht.
But I read the article and it makes sense also.I was also told and read a article saying never nadrolone and tren but I did and loved it so maybe test,primo and master would be good.

TweetMy next cycle is all together
Sustanon 750 mg weeks 1-18
Test prop 100 mg weeks 1-18 and test prop 400 mg weeks 19-20.
Primo 800 mg weeks 1-20
Injectable anadrol 25 mg EOD weeks 1-4
Npp 600 mg weeks 5-12
And tren ace 400 mg weeks 13-19
With aromasin 12.5 end
Hcg 250 iu two tomes a week.

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Originally Posted by chemicallyengineered

A receptor is like a switch, it is either on or off. No matter what the drug once the drug attaches to a receptor it is on. There are not separate receptors for different drugs, an androgen receptor is an androgen receptor.

some people cant seem to grasp this concept nor the anabolic threshold concept at all. that's why we have people that run 3-4-5g of compounds per week and look like normal dudes or are just normal skinny fat dudes

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Originally Posted by guns01

some people cant seem to grasp this concept nor the anabolic threshold concept at all. that's why we have people that run 3-4-5g of compounds per week and look like normal dudes or are just normal skinny fat dudes

So just to go back to this quote. The above post says that there is no such thing as tolerance with AAS? Am I reading that correctly?

TweetYes there is no "tolerance" but your body only has a certain number of receptors. Also because your body always seeks homeostasis your body will respond to all aas by increasing cortisol to shut down muscle growth. Your body looks at muscle like credit card debt, it's costs money(or in your body calories) to carry that muscle and your body doesn't want that extra cost. There are basically two ways o counteract the increased cortisol, take a break from aas and allow cortisol to lower naturally or increase your dose to again tip the scales towards growth. But then you have the issue of finishing returns. I have read but I do not have the link handy, that you teach almost 100% saturation at 4gms of aas per week. But that doesn't mean 1000mgs only gives 25% because saturation is not linear. The difference between 1000mgs and 2000mgs is a small difference in receptor saturation. But receptor saturation isn't the only way to get effects from aas. There are direct and indirect effects. I will cut and paste on that topic later on.