TweetPreloading does break down the rubber... I once preloaded a syrinfe and hid it in a puzzle box... Found it a few years later pulled back the plunger and the syringe turned comp[letely black... From that day forward i said id neveruse a preloaded syringe that was more than a day or so old... Ive been in sitiations ie vacation where i had to go a few weeks without it and the best I kinda did a frontload where i just did 2 weeks worth of gear before i left.... Not the best thing for stavle blood levels but with long esters you can shoot once a week if its necessary..... especially with things like deca and eq.... Test cyp and enanthat are ok but some test decanoate or undecanoate would be better..