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Originally Posted by mikeyg51

I love tren and I get sides at only 300 a per week...can't imagine dosages that high!

Same here I love it but its harsh on me. 1000 mg is crazy

TweetI actually had to quit it at about 400 or so a week of tren ace! I can run test all day and night but the tren kills me for some reason...love the effects on my body tho

TweetIMO that is very high, but has been done and can be done.

If done, Lowering test to 250 - 300mg while Tren is higher will yield the best results, as the androgens will not be fighting to bind to receptors, tren will take the majority leaving much less to freely circulate causing adverse sides.

TweetMay not be relevant, but I think it shows the potential effectiveness of some steroids over others when used together. I find it hard to believe that certain steroids are completely useless when used with other steroids due to the low affinity to bind with certain receptors. I know even the "weaker" steroids, still contribute in ways that a single steroid could not on its own.

Relative binding affinity of anabolic-androgenic steroids: comparison of the binding to the androgen receptors in skeletal muscle and in prostate, as well as to sex hormone-binding globulin.

Authors

Saartok T, Dahlberg E, Gustafsson JA.

Journal

Endocrinology. 1984 Jun;114(6):2100-6.

Affiliation

Abstract

It is unclear whether anabolic steroids act on skeletal muscle via the androgen receptor (AR) in this tissue, or whether there is a separate anabolic receptor. When several anabolic steroids were tested as competitors for the binding of [3H]methyltrienolone (MT; 17 beta-hydroxy-17 alpha-methyl-4,9,11-estratrien-3-one) to the AR in rat and rabbit skeletal muscle and rat prostate, respectively, MT itself was the most efficient competitor. 1 alpha-Methyl-5 alpha-dihydrotestosterone (1 alpha-methyl-DHT; mesterolone) bound most avidly to sex hormone-binding globulin (SHBG) [relative binding affinity (RBA) about 4 times that of DHT]. Some anabolic-androgenic steroids bound strongly to the AR in skeletal muscle and prostate [ RBAs relative to that of MT: MT greater than 19-nortestosterone ( NorT ; nandrolone) greater than methenolone (17 beta-hydroxy-1-methyl-5 alpha-androst-1-en-3-one) greater than testosterone (T) greater than 1 alpha-methyl-DHT]. In other cases, AR binding was weak (RBA values less than 0.05): stanozolol (17 alpha-methyl-5 alpha- androstano [3,2-c]pyrazol-17 beta-ol), methanedienone (17 beta-hydroxy-17 alpha-methyl-1,4-androstadien-3-one), and fluoxymesterolone (9 alpha-fluoro-11 beta-hydroxy-17 alpha-methyl-T). Other compounds had RBAs too low to be determined (e.g. oxymetholone (17 beta-hydroxy-2-hydroxymethylene-17 alpha-methyl-5 alpha-androstan-3-one) and ethylestrenol (17 alpha-ethyl-4- estren -17 beta-ol). The competition pattern was similar in muscle and prostate, except for a higher RBA of DHT in the prostate. The low RBA of DHT in muscle was probably due to the previously reported rapid reduction of its 3-keto function to metabolites, which did not bind to the AR [5 alpha-androstane-3 alpha, 17 beta-diol and its 3 beta-isomer (3 alpha- and 3 beta-adiol, respectively)]. Some anabolic-androgenic steroids (only a few synthetic) bound to SHBG (1 alpha-methyl-DHT much greater than DHT greater than T greater than 3 beta-adiol greater than 3 alpha-adiol = 17 alpha-methyl-T greater than methenolone greater than methanedienone greater than stanozolol). The ratio of the RBA in rat muscle to that in the prostate (an estimate of the myotrophic potency of the compounds) was close to unity, varying only between about 0.4 and 1.7 in most cases.

TweetI've ran 800mg of tren e a wk with 1g of test e for 14 weeks and the sides were unbearable. On the contrary I ran tren A at 700mg/wk with 250mg of test e wk and only side I got was night sweats.

TweetImo 1000mg of tren ace is way to much and the sides have to suck big time

TweetGreat inpu unclem that's crazy bro

Tweetwow guys..how you can handle over 300mg..mfg

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Originally Posted by anabolicpharma-eu.com

wow guys..how you can handle over 300mg..mfg

With a lil bit of gyno lmfao

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Originally Posted by anabolicpharma-eu.com

wow guys..how you can handle over 300mg..mfg

I try to keep it around 400mg/wk and 400mg test/ wk. With priviron I can keep the demons at bay.

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Originally Posted by rmewrench

I've ran 800mg of tren e a wk with 1g of test e for 14 weeks and the sides were unbearable. On the contrary I ran tren A at 700mg/wk with 250mg of test e wk and only side I got was night sweats.

This
Low test high tren makes tren enjoyable and the gains that much better.

Sent from my SAMSUNG-SGH-I747 using Tapatalk

Tweetbut still diet is most important guys

TweetI was at 3cc's of homebrew a day for about a month one time, each cc was approx 150mg. One of the worst periods of my life, ironically it was also the most phenomenal shape I've ever been in.

In no way worth the side effects. I think I slept maybe 30 mins a night... no more. Chalk it up to being young and stupid.

1000mg is a little high but should be ok. It is such a powerful hormone, even a little goes a tremendously long way.